Trazodone

Overview

  • EPIC Code:
  • LAB2639
  • Soft Test Code:
  • Send Out Test Code:
  • 1312
Alternate Names
  • Desyrel
  • TRAZO
Clinical Significance

For therapeutic drug monitoring of antidepressant therapy. Peak plasma levels occur approximately 1 hour after dosing when Trazodone is taken on an empty stomach or 2 hours after dosing when taken with food. Elimination of Trazodone is biphasic, consisting of an initial phase (half-life 3-6 hours) followed by a slower phase (half-life 5-9 hours).


Specimen Collection & Preparation

Specimen Requirements

2.0 mL Serum from a Red Top Tube in a Plastic Vial


Transport And Storage

14 days Ambient
14 days Refrigerated
12 months Frozen


Collection Instructions

Do not collect in a Serum Separator Tube (SST or PST)

Centrifuge and separate from cells immediately


Minimum Volume

1.2 mL


Neonatal Volume

Clinical Interpretation

Reference Range:

800 - 1600 mcg/L


Methodology:
  • Liquid Chromatography / Tandem Mass Spectrometry (LC-MS/MS)
Clinical Significance

For therapeutic drug monitoring of antidepressant therapy. Peak plasma levels occur approximately 1 hour after dosing when Trazodone is taken on an empty stomach or 2 hours after dosing when taken with food. Elimination of Trazodone is biphasic, consisting of an initial phase (half-life 3-6 hours) followed by a slower phase (half-life 5-9 hours).


Production Schedule

Days Performed
Tuesday
Thursday
Departments
  • Sendouts - Clinical
Turn Around Time

6 to 10 days


Coding & Compliance

CDM

01420957


CPT Coding

80338 (Medicare - G0480)