Last Modified:
3/16/2020 12:36:57 PM
Medical Necessity Documentation:
Client Notes:
Patient Preparation:
Specimen Requirements:
5.0 mL Whole Blood in a Lavender Top Tube - EDTA
Collection Instructions:
Minimum Volume:
3.0 mL Whole Blood
Transport & Storage: Temperature/Stability:
8 days Ambient (transport)
8 days Refrigerated
Rejection Criteria:
Gross hemolysis • Clotted blood • Received frozen
Reference Range:
Refer to Interpretive Results
Critical Ranges:
Test Comments:
Methodology:
Polymerase Chain Reaction (PCR) and Detection
Clinical Significance:
Plasma plasminogen activator inhibitor, PAI-1 is a major inhibitor of fibrinolysis. The 4G variant (AF386492.2:g.837del) in the PAI-1 (Serpine 1) gene promoter region is associated with an increase in the level of PAI-1 in plasma. Increased levels of PAI-1 in plasma may increase the risk for arterial and venous thrombosis, myocardial infarction, and progression of atherosclerosis and also recurrent spontaneous abortion.
Documentation:
Custom Panel:
No
PRODUCTION SCHEDULE
Turn Around Time:
12 to 18 days
Days Performed:
Wednesday
Sites Performed:
Quest - Chantilly to San Juan Capistrano
PHL Test Code:
4G5G
EPIC Test Code:
LAB2561
Send Out Test Code:
11368
Alternate Test Names:
PAI-1 4G/5G; Plasminogen Activator Inhibitor-1 4G/5G
Included Tests:
CPT Coding:
81400
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