Prostate Specific Antigen, Free and Total

Last Modified: 8/21/2023 1:37:51 PM


  Medicare Medical Necessity Restrictions May Apply
Medical Necessity Documentation:
Client Notes:  
Patient Preparation:  Patient should discontinue taking Biotin, Vitamin B7, or Vitamin H 48 hours before getting blood drawn

Specimen Requirements:

2.0 mL Serum in a SST Gold Top Tube
Collection Instructions: Do not collect specimen after a transrectal biopsy, results may be falsely elevated
Minimum Volume: 1.0 mL
Transport & Storage: Temperature/Stability:

48 hours Refrigerated
>48 hours Frozen
Rejection Criteria: Gross hemolysis • Gross lipemia • Grossly icteric
Reference Range:

Refer to Interpretive Report
Critical Ranges:  
Test Comments:  Patients taking vitamin supplements containing biotin doses of > 5 mg/day may have falsely decreased test results generated.
Methodology: Electrochmiluminescence Immunoassay (ECLIA)
Clinical Significance:

In men over 50 years with total PSA between 4.0 and 10.0 ng/mL, the percent (%) free PSA gives an estimate of the probability of cancer. In these circumstances the measurement of the % free PSA may aid in avoiding unnecessary biopsies.

Elevated levels of Prostate Specific Antigen (PSA) have been associated with benign and malignant prostatic disorders. Studies indicate that in men 50 years or older measurement of PSA is a useful addition to the digital rectal exam in the early detection of prostate cancer. In addition, PSA decreases to undetectable levels following complete resection of the tumor and may rise again with recurrent disease or persist with residual disease. Thus, PSA levels may be of assistance in the management of prostate cancer patients.
Documentation:  
Custom Panel: No

PRODUCTION SCHEDULE

Turn Around Time: 3 to 5 days
Days Performed: Sunday, Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed: Parkview Regional Medical Center
PHL Test Code: PSFT
EPIC Test Code: LAB171
Alternate Test Names: Fractionated PSA; Free PSA and Total PSA; PSA Free and Total; PSA II; PSA, Free and Total; T/F PSA
Included Tests: % Free PSA calculated ; PSA Free; PSA Total
CPT Coding: 84153, 84154

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