Medical Necessity Documentation:
Client Notes:
Patient Preparation:
Specimen Requirements:
1.0 mL Serum from a Red Top Tube in a Plastic Vial
Collection Instructions:
Minimum Volume:
0.7 mL
Transport & Storage: Temperature/Stability:
72 hours Ambient
14 days Refrigerated
30 days Frozen
Rejection Criteria:
Hemolysis • Lipemia • Microbially contaminated
Reference Range:
Critical Ranges:
Test Comments:
If AChR blocking is <15% of inhibition, AChR binding is ≤0.30 nmol/L, and AChR modulating is <32% binding inhibition, then MuSK Antibody Test will be performed at an additional charge
Methodology:
Immunoassay (IA)
Clinical Significance:
Myasthenia Gravis Panel 2 with Reflex to MuSK Antibody - Myasthenia gravis (MG) is an autoimmune disorder affecting the neuromuscular junction. 80% of patients with generalized MG have serum antibodies to AChR - Blocking, Binding, or Modulating. Antibodies to MuSK make up a variable proportion of the remaining 20%.
Documentation:
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes
Custom Panel:
No
PRODUCTION SCHEDULE
Turn Around Time:
8 days
Days Performed:
Monday, Tuesday, Wednesday, Thursday, Friday
Sites Performed:
Quest - Chantilly to San Juan Capistrano
PHL Test Code:
MGP2
EPIC Test Code:
IMO5706
Send Out Test Code:
93859
Included Tests:
Acetylcholine Receptor Blocking Antibody, Acetylcholine Receptor Binding Antibody, *Acetylcholine Receptor Modulating Antibody
CPT Coding:
86041, 86042, 86043 with reflex to 86366