Last Modified:
3/1/2022 6:21:34 AM
Medical Necessity Documentation:
Client Notes:
Patient Preparation:
Specimen Requirements:
1.5 mL Serum from a Red Top Tube in a Plastic Vial
Collection Instructions:
Minimum Volume:
1.0 mL Serum
Transport & Storage: Temperature/Stability:
7 days Ambient
14 days Refrigerated
21 days Frozen
Reference Range:
Phospholipase A2 Receptor (PLA2R) Ab, ELISA
| RU/mL |
|
| <14 |
Negative |
| 14-19 |
Borderline |
| >19 |
Positive |
Phospholipase A2 Receptor (PLA2R) Ab, IFA - Negative
Critical Ranges:
Test Comments:
Methodology:
Enzyme Linked Immunosorbent Assay (ELISA) • Immunofluorescence Assay (IFA)
Clinical Significance:
Phospholipase A2 Receptor (PLA2R) Antibody (Ab) testing provides physicians with a non-invasive tool for diagnosing primary membranous nephritis (PMN), an autoimmune disease most commonly mediated by autoantibodies to the podocyte antigen, PLA2R. PLA2R Ab is a highly specific biomarker for PMN and is detected in about 70-80% of patients. Moreover, PLA2R Ab levels frequently rise and fall with the clinical course of PMN and PLA2R Ab levels may have clinical utility in monitoring PMN patients for therapeutic response, remission, and disease relapse.
Documentation:
Custom Panel:
No
PRODUCTION SCHEDULE
Turn Around Time:
4 to 6 days
Days Performed:
Tuesday, Thursday, Saturday
Sites Performed:
Quest - Chantilly to San Juan Capistrano
PHL Test Code:
PLA2R
EPIC Test Code:
IMO5579
Send Out Test Code:
93875
Alternate Test Names:
Anti-PLA2R; Glomerulonephritis; Idiopathic Membranous Nephropathy; Membranous Nephropathy; Phospholipase A2 Receptor (PLA2R) Antibody Panel; PLA2R; PLA2R Antibodies; Primary Membranous Nephropathy
Included Tests:
Phospholipase A2 Receptor (PLA2R) Antibody, ELISA; Phospholipase A2 Receptor (PLA2R) Antibody, IFA
CPT Coding:
83520, 86255
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