Parkview Health Laboratory: Test Directory

Medical Necessity Documentation:

Patient Preparation: Patient should discontinue taking Biotin, Vitamin B7, or Vitamin H 48 hours before getting blood drawn.

Specimen Requirements:

2.0 mL Plasma in a PST Mint Green Top Tube - Li Heparin

Collection Instructions:

Minimum Volume: 0.2 mL Plasma

Transport & Storage: Temperature/Stability:

24 hours Refrigerated
12 months Frozen

Rejection Criteria: Serum; Hemolysis

Reference Range: Male:
0 - 15 ng/L

Female:
0-10 ng/L

Algorithm for use with Troponin T, Generation 5

To determine if a patient may have had a myocardial infarction, Troponin T, Generation 5 will be performed at zero and 2 hours.

If both the zero hour and 2-hour result is < 10 ng/L for women or < 15 ng/L for men and the 2-hour change is:

<4 ng/L	Cardiac injury is not indicated
> 4 ng/L and <10 ng/L	The result is abnormal. Cannot rule out myocardial injury. Repeat test in 2 hours.
> 10 ng/L	Suspicious for myocardial infarction (MI). Recommend clinical correlation.

If either the zero hour or the 2-hour result is >10 ng/L for women or >15 ng/L in men and the 2-hour change is:

<4 ng/L	The result is abnormal. Mostly suggestive of chronic myocardial injury or possible late MI.
> 4 ng/L and <10 ng/L	The result is abnormal. Cannot rule out MI. Repeat testing in 2 hours.
> 10 ng/L	Consistent with MI if clinical characteristics correlate.

Critical Ranges: >100 ng/L

Test Comments: Patients taking vitamin supplements containing doses of >5 mg/day may have falsely decreased test results generated.

Methodology: Electrochemiluminescence Immunoassay

Clinical Significance: Troponin T is a regulatory protein released when cardiac cell necrosis occurs. It is not normally present in blood unless cardiac damage has occurred. Troponin T frequently appears in serum as early as one to three hours after the onset of myocardial infarction and remains elevated for 10-14 days. In cases of unstable angina and acute myocardial infarction with minimal cardiac damage, low elevations of CK and CK-MB are difficult to interpret; measurement of serum troponin T is a useful diagnostic aid in such patients

Documentation:

Custom Panel: No

Stat Eligible: Yes

Turn Around Time: 1 hour

Days Performed: Sunday, Monday, Tuesday, Wednesday, Thursday, Friday, Saturday

Sites Performed: Parkview Dekalb Hospital, Parkview Huntington Hospital, Parkview LaGrange Hospital, Parkview Noble Hospital, Parkview Randallia Hospital, Parkview Regional Medical Center, Parkview Southwest , Parkview Wabash Hospital, Parkview Warsaw , Parkview Whitley Hospital

PHL Test Code: TNT5

EPIC Test Code: LAB3111

Included Tests:

CPT Coding: 84484

Parkview Laboratory: Test Directory

Troponin T, 5th Generation

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