Last Modified:
6/14/2019 4:06:12 PM
Medical Necessity Documentation:
Client Notes:
Patient Preparation:
Patient Preparation: Avoid contact of samples with plasticizers, varnishes, paint fumes, and fatty acids. Collect as a trough just before next dose (Optimum time to collect sample: 1 hour before next dose
Specimen Requirements:
1.0 mL Serum from a Red Top Tube in a Plastic Vial
Collection Instructions:
Specimen should be drawn 30 minutes prior to next dose
Centrifuge and immediately separate serum or plasma specimens from the cells
Minimum Volume:
0.5 mL
Transport & Storage: Temperature/Stability:
7 days Refrigerated
30 days Frozen
Rejection Criteria:
Collection in a Serum Separator Tube (SST or PST)
Reference Range:
4.8 - 17.3 mg/L
Critical Ranges:
Test Comments:
Methodology:
Immunoassay
Clinical Significance:
Analysis of Free Valproic Acid levels may be useful in delineating the cause of toxicity when the total concentration is not excessive. Geriatric patients often exhibit hypoalbuminemia, which results in a marked decrease in protein-binding sites for drugs. The clinical symptoms of drug intoxication may not be apparent, but may manifest themselves in impaired cognitive function and confusion. Therefore, it is important to evaluate both total and free concentrations
Documentation:
Custom Panel:
No
PRODUCTION SCHEDULE
Turn Around Time:
2 to 3 days
Days Performed:
Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed:
Quest - Valencia
PHL Test Code:
FVPA
EPIC Test Code:
LAB2590
Send Out Test Code:
3314
Included Tests:
CPT Coding:
80165
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