Last Modified:
7/15/2016 7:35:16 AM
Specimen Requirements:
1.0 mL Random Urine
Minimum Volume:
0.5 mL Urine
Transport & Storage: Temperature/Stability:
72 hours Ambient
14 days Refrigerated
30 days Frozen
Reference Range:
Nicotine
| Smokers |
200-700 ng/mL |
| Nonsmokers |
≤17 ng/mL |
Cotinine
| Smokers |
300-1300 ng/mL |
| Nonsmokers |
≤20 ng/mL |
Methodology:
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
Clinical Significance:
This assay is used for the detection of nicotine and cotinine in urine to determine the tobacco exposure status of the individual. Nicotine has a short half-life of approximately forty minutes; Its presence may indicate recent tobacco exposure. Cotinine, the major nicotine metabolite, has a half-life of 24 hours and is detectable for several days after cessation of tobacco exposure.
Custom Panel:
No
PRODUCTION SCHEDULE
Turn Around Time:
3 to 4 days
Days Performed:
Sunday, Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed:
Quest - Chantilly
PHL Test Code:
MSOT
EPIC Test Code:
Send Out Test Code:
90646
Alternate Test Names:
Nicotine and Cotinine, LC/MS/MS, Urine
CPT Coding:
80323
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