Streptococcus pneumoniae IgG Ab Panel (14 Serotypes), MAID

Overview

  • EPIC Code:
  • LAB2639
  • Soft Test Code:
  • Send Out Test Code:
  • 19564
Alternate Names
  • Pneumo Ab Titer
  • SPNE
  • Streptococcus pneumoniae IgG Antibodies
  • Streptococcus pneumoniae IgG Antibody Panel (14 Se
Included Tests

Streptococcus pneumonias Type 1 Antibodies; Streptococcus pneumonias Type 3 Antibodies; Streptococcus pneumonias Type 4 Antibodies; Streptococcus pneumonias Type 5 Antibodies; Streptococcus pneumonias Type 6B Antibodies; Streptococcus pneumonias Type 7F Antibodies; Streptococcus pneumonias Type 8 Antibodies; Streptococcus pneumonias Type 9N Antibodies; Streptococcus pneumonias Type 9V Abs; Streptococcus pneumonias Type 12F Antibodies; 
Streptococcus pneumonias Type 14 Antibodies; Streptococcus pneumonias Type 18C Antibodies; 
Streptococcus pneumonias Type 19F Antibodies; Streptococcus pneumonias Type 23F Antibodies


Clinical Significance

Determination of IgG antibody concentrations to 14 different Streptococcus pneumoniae polysaccharide-specific serotypes 1, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 12F, 14, 18C, 19F, and 23F.


Specimen Collection & Preparation

Specimen Overview

Pre and Post samples should be tested together on the same run to avoid variation in results caused by lot-to-lot and inter-assay variation.

It is recommended that two Pre tubes be drawn. Save one Pre serum Frozen.

The other can be sent to determine the need to vaccinate.

If the patient already has protective values, there is no need to revaccinate and test a Post sample.

If Pre results do not show protective values, send the saved pre sample together with the Post vaccination sample.

Specimen Requirements:

-OR-

2.0 mL Serum from a Red Top Tube in a Plastic Vial
Minimum Volume:
1.0 mL Serum *

* This volume does not allow for repeat testing

Transport and Storage:
  • Ambient: 7 Days
  • Refrigerated: 14 Days
  • Frozen (-20 C or colder): 2 Months

Clinical Interpretation

Reference Range:

Streptococcus pneumonias 
Type 1 Antibodies: > 1.0 ug/mL 
Type 3 Antibodies: > 1.0 ug/mL 
Type 4 Antibodies: > 1.0 ug/mL 
Type 5 Antibodies: > 1.0 ug/mL 
Type 6B Antibodies: > 1.0 ug/mL 
Type 7F Antibodies: > 1.0 ug/mL 
Type 8 Antibodies: > 1.0 ug/mL 
Type 9N Antibodies: > 1.0 ug/mL 
Type 9V Abs: > 1.0 ug/mL 
Type 12F Antibodies: > 1.0 ug/mL 
Type 14 Antibodies: > 1.0 ug/mL 
Type 18C Antibodies: > 1.0 ug/mL 
Type 19F Antibodies: > 1.0 ug/mL 
Type 23F Antibodies: > 1.0 ug/mL 
 

S. pneumoniae IgG: Greater than 1.0 ug/mL . . . . Protective Level 


Test Comments:

All serum specimens are pre-treated with Pneumococcal Cell-Wall Polysaccharide (C-PS) to remove anti-C-PS specific antibody


Methodology:
  • Multi-Analyte Immunodetection (MAID)
Clinical Significance

Determination of IgG antibody concentrations to 14 different Streptococcus pneumoniae polysaccharide-specific serotypes 1, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 12F, 14, 18C, 19F, and 23F.


Production Schedule

Sites Performed
  • Quest - Chantilly to San Juan Capistrano
Days Performed
Tuesday
Friday
Departments
  • Sendouts - Clinical
Turn Around Time

5 to 8 days


Coding & Compliance

CPT Coding

86581