Histoplasma Antibody, CSF

Overview

  • EPIC Code:
  • LAB2639
  • Soft Test Code:
  • MSOT
  • Send Out Test Code:
  • 5297
Alternate Names
  • Histoplasma Ab, Complement Fixation, CSF
  • Histoplasma, CSF (CF)
Included Tests

 Mycelial Phase Antibody; Yeast Phase Antibody


Clinical Significance

Central nervous system infection occurs in up to 25% of patients with subacute progressive disseminated histoplasmosis. Detection of antibodies in CSF can serve as a useful tool for identifying these patients.


Specimen Collection & Preparation

Test Notes

If multiple Fluid or CSF tests are being requested please specify order of importance


Specimen Requirements:

-OR-

1.0 CSF in a Sterile Plastic Vial
Minimum Volume:
0.5 mL CSF*

* This volume does not allow for repeat testing

Rejection Criteria:

Gross hemolysis

Grossly icteric


Transport and Storage:
  • Ambient (18-24°C): 7 Days

    Transport 

  • Refrigerated (2-8°C): 14 Days
  • Frozen (-20° C or colder): 30 Days

Clinical Interpretation

Reference Range:

Yeast Phase Antibody <1:1 titer
Mycelial Phase Antibody <1:1 titer


Interpretive Criteria

<1:1 Antibody Not Detected
≥1:1 Antibody Detected


Methodology:
  • Complement Fixation (CF)
Clinical Significance

Central nervous system infection occurs in up to 25% of patients with subacute progressive disseminated histoplasmosis. Detection of antibodies in CSF can serve as a useful tool for identifying these patients.


Production Schedule

Sites Performed
  • Quest - Chantilly
Days Performed
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Departments
  • Sendouts - Miscellaneous
Turn Around Time

2 to 3 days


Coding & Compliance

CDM

00913333


CPT Coding

86317 (x2)