Isohemagglutinin Titer

Overview

  • EPIC Code:
  • MISC
  • Soft Test Code:
  • MSOT
  • Send Out Test Code:
  • 096164
Alternate Names
  • Anti-A Titer
  • Anti-B Titer
  • Isohemagglutinins
Included Tests

Antibody Screen; Anti-A titer; Anti-B titer; Blood grouping (ABO)


Clinical Significance

Determine the titer of isohemagglutinins (anti-A and/or anti-B) in serum; the absence of expected isohemagglutinins may suggest an immunological deficiency. This test is not recommended for the determination of immunodeficiency. Dependent upon a variety of factors, normal titers are >1:8.

The presence of cold agglutinins other than anti-A and anti-B may interfere with test interpretation. Newborns, infants younger than six months of age, and patients who have undergone immunosuppressive therapy may not demonstrate expected ABO isohemagglutinins.


Specimen Collection & Preparation

Specimen Requirements:

-OR-

4.0 mL Whole Blood in a Lavender Top Tube - EDTA
Minimum Volume:
3.0 mL Whole Blood in a Lavender Top Tube - EDTA*

* This volume does not allow for repeat testing

Rejection Criteria:

Gross Hemolysis

Bacterial or other contamination


Transport and Storage:
  • Refrigerated:

Clinical Interpretation

Reference Range:

 See Interpretive Report


Methodology:
  • Hemagglutination
Clinical Significance

Determine the titer of isohemagglutinins (anti-A and/or anti-B) in serum; the absence of expected isohemagglutinins may suggest an immunological deficiency. This test is not recommended for the determination of immunodeficiency. Dependent upon a variety of factors, normal titers are >1:8.

The presence of cold agglutinins other than anti-A and anti-B may interfere with test interpretation. Newborns, infants younger than six months of age, and patients who have undergone immunosuppressive therapy may not demonstrate expected ABO isohemagglutinins.


Production Schedule

Sites Performed
  • LabCorp
Departments
  • Sendouts - Clinical
Turn Around Time

3 to 5 days


Coding & Compliance

CDM

00913334


CPT Coding

86940