Leptin

Overview

  • EPIC Code:
  • LAB2639
  • Soft Test Code:
  • MSOT
  • Send Out Test Code:
  • 90367
Clinical Significance

Leptin is an adipocyte-derived hormone that is essential for normal body weight regulation. Leptin production is under neuroendocrine control so that serum concentrations vary directly with the amount of triglycerides stored in adipose tissue depots.


Specimen Collection & Preparation

Specimen Requirements:

-OR-

1.0 mL Serum from a Red Top Tube in a Plastic Vial 
Minimum Volume:
0.2 mL Serum*

* This volume does not allow for repeat testing

Rejection Criteria:

Moderate hemolysis

Gross hemolysis

Hypericteric specimens


Transport and Storage:
  • Ambient (18-24°C): 8 Hours
  • Refrigerated (2-8°C): 14 Days

    Transport 

    Cold Packs

  • Frozen (-20° C or colder): 35 Days

Clinical Interpretation

Reference Range:

Pediatric male and female

5-9.9 Years 0.6-16.8 ng/mL
10-13.9 Years 1.4-16.5 ng/mL
14-17.9 Years 0.6-24.9 ng/mL


Adult Lean Subjects (18-71 Years) with BMI range of 18-25

Male 0.3-13.4 ng/mL
Female 4.7-23.7 ng/mL


Adult Subjects (19-60 Years) with BMI range of 25-30

Male 1.8-19.9 ng/mL
Female 8.0-38.9 ng/mL


Methodology:
  • Electrochemiluminescence (ECL)
Clinical Significance

Leptin is an adipocyte-derived hormone that is essential for normal body weight regulation. Leptin production is under neuroendocrine control so that serum concentrations vary directly with the amount of triglycerides stored in adipose tissue depots.


Production Schedule

Sites Performed
  • Quest - Chantilly to San Juan Capistrano
Days Performed
Monday
Thursday
Departments
  • Sendouts - Miscellaneous
Turn Around Time

4 to 8 days


Coding & Compliance

CDM

00913333


CPT Coding

83520