Coenzyme Q10

Last Modified: 2/20/2019 3:27:32 PM


Medical Necessity Documentation:  
Client Notes:  
Patient Preparation: 8 to 12 hours Fasting; 

Patient may have water. 

It is not necessary to discontinue nutritional supplements before this test.
Specimen Requirements: 1.0 mL Serum in a SST Gold Top Tube in Amber Vial
Collection Instructions: Protect from Light by placing the serum in an Amber Vial

Freeze and ship frozen
Minimum Volume: 0.5 mL
Transport & Storage: Temperature/Stability: 7 days Frozen
Rejection Criteria: Ambient and Refrigerated Unacceptable
Reference Range: Coenzyme Q10: 0.50 - 1.50 mg/L
Therapeutic range for cardiovascular disease: > 2.50 mg/L
95% Reference Interval: 0.40 - 2.30
Critical Ranges:  
Test Comments:  
Methodology: High Performance Liquid Chromatography
Clinical Significance: Coenzyme Q10 (CoQ10) is a fat soluble cofacter that is essential for energy producing metabolic pathways and for the proper functioning of the mitochondrial oxidative system. With insufficient CoQ10, the electron transfer activity of the mitochondria decreases, resulting in a net failure to produce the energy necessary to run the cell. Tissues with high energy demand have even greater demands for CoQ10. For example, heart muscle, which continually exerts a pumping action for an entire lifetime, has an immense need for the cofactor. Studies demonstrate the effectiveness of supplemental coenzyme Q10 in cardiomyopathy, myocardial dysfunction, and congestive heart failure. CoQ10 is also a powerful antioxidant like vitamins E and C, and thus serves the role of neutralizing excess free radicals. It is now well established that the control of excessive free radical activity is key in preventing/delaying the progression of degenerative diseases.
Documentation:  
Custom Panel: No

PRODUCTION SCHEDULE

Turn Around Time: 5 to 8 days
Days Performed: Sunday, Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed: Quest - Chantilly
PHL Test Code: CQ10
EPIC Test Code: LAB2543
Send Out Test Code: 19826X / 198268
Included Tests:  
CPT Coding: 82491

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