Helicobacter pylori Antigen Stool

Overview

  • EPIC Code:
  • LAB2596
  • Soft Test Code:
  • HPST
  • Send Out Test Code:
  • 34838
Alternate Names
  • H Pylori Stool Antigen
  • H-Pylori Stool Antigen
  • H. Pylori Stool Antigen
Clinical Significance

Colonization with H. pylori is associated with increased risk of patients developing gastritis, peptic ulcer disease, and gastric adenocarcinoma. Stool antigen testing provides a sensitive measure of infection including during and after treatment


Specimen Collection & Preparation

Patient Preparation

For initial diagnostic purposes no special patient preparation is required. Patients are not required to be off of medications or to fast before this test. While positive test results from patients taking agents such as proton pump inhibitors and antimicrobials should be considered accurate, false negative results may be obtained. For this reason, physicians may suggest the patient go off medications for two weeks and repeat test if negative results are obtained. To confirm eradication, testing should be done at least 4 weeks following the completion of treatment. However, a positive test result 7 days post therapy is indicative of treatment failure. This test is cleared for use with specimens from pediatric patients.


Specimen Requirements:

-OR-

0.5 mL or grams of fresh Stool
Specimen Information:


Collection Instructions:

Commode hat for collection

Collect 0.5 mL or 0.5 grams of liquid or semi-solid stool 

or

20 mm diameter solid stool 


Processing Instructions:

Transfer to properly labeled plastic, leak-proof container


Rejection Criteria:

Stool received in or mixed with preservative

Stool received in a transport media

Stool collected on a swab


Transport and Storage:
  • Ambient: 2 Hours
  • Refrigerated: 72 Hours
  • Frozen (-20 C or colder): 30 Days

    Prefered

Clinical Interpretation

Reference Range:

Negative


Methodology:
  • Lateral Flow Immunoassay
Clinical Significance

Colonization with H. pylori is associated with increased risk of patients developing gastritis, peptic ulcer disease, and gastric adenocarcinoma. Stool antigen testing provides a sensitive measure of infection including during and after treatment


Production Schedule

Sites Performed
  • Parkview Regional Medical Center
Days Performed
Monday
Tuesday
Wednesday
Thursday
Friday
Departments
  • Immunology
Turn Around Time

3 to 7 days


Coding & Compliance

CDM

00911086


CPT Coding

87338