Estrone

Last Modified: 2/19/2024 8:45:36 AM


Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:  
Specimen Requirements: 0.5 mL Serum from a Red Top Tube in a Plastic Vial
Collection Instructions: Order must and specimen must specify age and gender. 

Note: Norethindrone acetate/Norethisterone acetate is known to interfere with the measurement of estrone using the Quest Diagnostics LC-MS/MS method. This test should not be used to quantitate estrone in patients taking this drug.
Minimum Volume: 0.25 mL Serum
Transport & Storage: Temperature/Stability: Room temperature: 5 days
Refrigerated: 7 days (transport)
Frozen: 28 days
Rejection Criteria: Serum Separator Tube (SST®) • Gross hemolysis
Reference Range:

Adult    
Female    
  Follicular Stage 10-138 pg/mL
  Luteal Stage 16-173 pg/mL
  Postmenopausal ≤65 pg/mL
Male ≤68 pg/mL

Pediatric Male (pg/mL) Female (pg/mL)
Pre-pubertal (1-9 Years) <10 ≤34
10-11 Years ≤12 ≤72
12-14 Years ≤28 ≤75
15-17 Years ≤64 ≤188

Critical Ranges:  
Test Comments: *ERT= Estrogen Replacement Therapy
Methodology: Chromatography / Mass Spectrometry
Clinical Significance: Estrone is primarily derived from metabolism of androstenedione in peripheral tissues, especially adipose tissues. Individuals with obesity have increased conversion of androstenedione to Estrone leading to higher concentrations. In addition, an increase in the ratio of Estrone to Estradiol may be useful in assessing menopause in women
Documentation:  
Custom Panel: No

PRODUCTION SCHEDULE

Turn Around Time: 2 to 5 days
Days Performed: Sunday, Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed: Quest - Chantilly to San Juan Capistrano
PHL Test Code: ESTR
EPIC Test Code: LAB982
Send Out Test Code: 23244
Alternate Test Names: E1
Included Tests:  
CPT Coding: 82679

Go back to the top of the page.