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Insulin Autoantibody
Last Modified:
8/7/2019 10:38:32 AM
Medical Necessity Documentation:
Client Notes:
Patient Preparation:
Specimen Requirements:
1.0 mL Serum from a
Red Top Tube
in a Plastic Vial
Collection Instructions:
Avoid Hemolysis and Lipemia
Minimum Volume:
0.2 mL
Transport & Storage: Temperature/Stability:
28 days Ambient
28 days Refrigerated
28 days Frozen
Reference Range:
Refer to Interpretive Results
Critical Ranges:
Test Comments:
Methodology:
Radiobinding Assay
Clinical Significance:
Type 1 diabetes is characterized by a lymphocytic cell infiltrate of the pancreatic islets. Insulin Antibody is useful in assessing lower titers of autoantibody in patients with diabetes, detecting insulin autoantibody in patients who are ''prediabetic,'' and in detecting autoantibody in patients with other autoimmune disorders.
Measurement of GAD-65, ICA-512, and Insulin Antibody is a highly sensitive means to assess risk and predict onset of Type I diabetes. There is a correlation between the number of positive antibodies and the antibody titers versus the severity of the autoimmune process.
Documentation:
Custom Panel:
No
PRODUCTION SCHEDULE
Turn Around Time:
4 to 7 days
Days Performed:
Monday, Wednesday, Friday
Sites Performed:
Quest - Chantilly
PHL Test Code:
INSA
EPIC Test Code:
IMO91
Send Out Test Code:
36178
Included Tests:
CPT Coding:
86337
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