Methylmalonic Acid, Urine

Last Modified: 6/17/2019 2:55:02 PM

Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:  
Specimen Requirements:

1.7 mL Urine in a Plastic Container

Collection Instructions: Unpreserved
Minimum Volume: 2.0 mL
Transport & Storage: Temperature/Stability: 4 days Ambient
12 days Refrigerated (Preferred) transport
30 days Frozen (-20)
90 days Frozen (-70)
Rejection Criteria: Received room temperature • Acidified urine
Reference Range:
Methylmalonic Acid, Urine 0.3-1.9 mmol/mol creat
Creatinine, Random Urine
0-6 Months 0.18-2.48 mmol/L 
7-11 Months 0.18-2.74 mmol/L
1-2 Years 0.18-9.72 mmol/L
3-8 Years 0.18-11.49 mmol/L
9-12 Years 0.18-14.14 mmol/L
Adult 1.77-23.31 mmol/L
Critical Ranges:  
Test Comments:  
Methodology: Gas Chromatography/Tandem Mass Spectrometry (GC/MS/MS)
Clinical Significance:

Methylmalonic Acid (MMA) is useful to diagnose and monitor Vitamin B12 (cobalamin) deficiency, and to diagnose and monitor patients with methylmalonic acidemia

Custom Panel: No


Turn Around Time: 3 to 6 days
Days Performed: Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed: Quest - Chantilly to San Juan Capistrano
PHL Test Code: UMETU
EPIC Test Code: LAB3057
Send Out Test Code: 91032
Alternate Test Names: Methylmalonic Acid, GC/MS/MS, Urine; MMA; MMA, Urine
Included Tests: Creatinine; Methylmalonic Acid
CPT Coding: 82570, 83921

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