Special Collection Kit 
   
One (1) 6.0 mL Whole Blood in Clear Red Top Tube - No Additive
Two (2) 2.0 mL Whole Blood Dark Blue Top Tubes - 9NC Coagulation Sodium Citrate 3.2%

Specimens to be collected with a 21g needle only.  
    (Specimen may be collected from a PICC line if a 21G or large bore needle is used, must have a minimum of 5.0 mL whole blood discarded prior to kit collection)

Do Not Uncap Tubes 
*Collect any additional blood tests ordered after this kit is drawn

Click here for collection instructions: 
 1. Read all instructions before collecting samples. Collect specimens using 21 g needle only. Do Not Uncap tubes. Collect addition blood tests after this kit is drawn. 
 2. Collect all tubes in number order 1-3. Blue-Top tubes are 2mL draw fill to black line (1/2 full). Do not underfill. 
 3. Gently invert tubes 5 times Do Not create bubbles. 
 4. Label tubes with patient name, DOB, date and time of collection, and collectors employee id. Return kit tubes to original baggie. Send any additional tubes collected separately. Do Not Refrigerated. 
 5. Hand deliver STAT to lab. Do Not send via pneumatic tube system (CTS). Specimen must be in PRMC Lab within 3 hours of draw.

PRU=P2Y12 Reaction Units P2Y12 Platelet Reactivity is intended to measure the level of platelet P2Y12 receptor blockage resulting from P2Y12 receptor blocker drugs, such as clopidogrel and prasugrel. The PRU reference range in P2Y12 receptor blocker drug-naive population is 182-335, according to manufacturer's package insert. In general, PRU values lower than 180 are associated with expected antiplatelet effect. Factors that contribute to an inadequate response are drug interactions, underlying health conditions, non-compliance, and inherent platelet disorders. Drug response is also dependent on dosage and timing of testing. Patients taking P2Y12 inhibitors are at increased risk of perioperative bleeding due to platelet dysfunction from drug effect. It is recommended to discontinue use of P2Y12 drugs for 5-7 days prior to surgery to allow restoration of platelet function. PRU values greater than or equal to 180 are indication of no drug effect. This assay does not test aspirin drug response or platelet dysfunction unrelated to P2Y12 receptor blockage. Clinical decisions cannot be based solely upon this test result.