Everolimus, Blood

Last Modified: 5/30/2019 9:33:33 AM

Client Notes: Drug regimens are to be noted on requisition: Time and date of drug administration
Specimen Requirements: 2.0 mL Whole Blood in a Lavender Top Tube - EDTA
Collection Instructions: Specimen should be drawn immediately prior to am dose
Minimum Volume: 1.0 Whole Blood
Transport & Storage: Temperature/Stability: 7 days Ambient (transport)
14 days Refrigerated
30 days Frozen
Rejection Criteria: Gel barrier tubes • Clotted specimens
Reference Range:
Trough 3.0-8.0 ng/mL for Transplantation
Trough 5.0-10.0 ng/mL for Oncology/Neurology
Test Comments: Therapeutic range applies to trough specimens drawn just prior to a.m. dose. 

Symptoms of toxicity are more likely to occur at trough levels exceeding 12.0 ng/mL
Methodology: Chromatography/Mass Spectrometry
Clinical Significance: Everolimus is an immunosuppresive drug used in organ transplantation to prevent graft rejection. Therapeutic drug monitoring is useful to optimize dose and avoid toxicity
Custom Panel: No


Turn Around Time: 1 to 2 days
Days Performed: Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed: Quest - Chantilly
PHL Test Code: MSOT
EPIC Test Code: MISC
Send Out Test Code: 18883
CPT Coding: 80169

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