Everolimus is an immunosuppresive drug used in organ transplantation to prevent graft rejection. Therapeutic drug monitoring is useful to optimize dose and avoid toxicity
Drug regimens are to be noted on requisition: Time and date of drug administration
2.0 mL Whole Blood in a Lavender Top Tube - EDTA
7 days Ambient (transport)
14 days Refrigerated
30 days Frozen
Specimen should be drawn immediately prior to am dose
1.0 Whole Blood
| Trough | 3.0-8.0 ng/mL for Transplantation |
| Trough | 5.0-10.0 ng/mL for Oncology/Neurology |
Therapeutic range applies to trough specimens drawn just prior to a.m. dose.
Symptoms of toxicity are more likely to occur at trough levels exceeding 12.0 ng/mL
Everolimus is an immunosuppresive drug used in organ transplantation to prevent graft rejection. Therapeutic drug monitoring is useful to optimize dose and avoid toxicity
1 to 2 days
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