Herpes Simplex Virus 1 IgG, Type Specific Antibody

Last Modified: 2/23/2021 11:03:40 AM


Specimen Requirements:

1.0 mL Serum from a Red Top Tube in a Plastic Vial

Minimum Volume: 0.5 mL Serum
Transport & Storage: Temperature/Stability: 7 days Ambient (transport)
14 days Refrigerated
30 days Frozen
Rejection Criteria: Gross hemolysis • Grossly lipemic • Plasma • No Gel
Reference Range:
Index Interpretation
<0.90 Negative
0.90-1.09 Equivocal
>1.09 Positive
Test Comments: This assay utilizes recombinant type-specific antigens to differentiate HSV-1 from HSV-2 infections. A index positive result cannot distinguish between recent and past infection. If recent HSV infection is suspected but the results are negative or equivocal, the assay should be repeated in 4-6 weeks. The performance index characteristics of the assay have not been established for pediatric populations, immunocompromised patients, or neonatal screening
Methodology: Immunoassay
Clinical Significance: Herpes Simplex Virus (HSV) is responsible for several clinically significant human viral diseases, with severity ranging from inapparent to fatal. Clinical manifestations include genital tract infections, neonatal herpes, meningoencephalitis, keratoconjunctivitis, and gingivostomatitis. There are two HSV serotypes that are closely related antigenically. HSV type 2 is more commonly associated with genital tract and neonatal infections, while HSV type 1 is more commonly associated with infections of non-genital sites. Specific typing is not usually required for diagnosis or treatment. The mean time to seroconversion using the type specific assay is 25 days. The performance of this assay has not been established for use in a pediatric population, for neonatal screening, or for testing of immunocompromised patients
Custom Panel: No

PRODUCTION SCHEDULE

Turn Around Time: 1 to 2 days
Days Performed: Sunday, Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed: Quest - Chantilly
PHL Test Code: MSOT
EPIC Test Code:
Send Out Test Code: 3636
Alternate Test Names: HerpeSelect; HSV IgG; HSV Type 1 IgG
CPT Coding: 86695

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