Metanephrines, Fractionated Urine

Overview

  • EPIC Code:
  • MISC
  • Soft Test Code:
  • MSOT
  • Send Out Test Code:
  • 149618
Alternate Names
  • Metanephrines, Fractionated Urine Random
Included Tests

Creatinine; Metanephrines; Normetanephrines; Total Metanephrines; 


Clinical Significance

Useful in the evaluation of pheochromocytoma


Specimen Collection & Preparation

Patient Preparation

If possible, patients should discontinue all drugs at least 1 week prior to collection. Medications that can interfere with the assay include: L-DOPA, Alpha-methyldopa (Aldomet), Buspirone, Codeine, Isoetharine, Isoproterenol, Mandelamine, Metoclopramide, Acetaminophen (high concentrations only), Labetalol, Catecholamine-containing drugs, MAO inhibitors, diuretics and vasodilators.


Specimen Requirements

5.0 mL Random Urine in a  Non-Sterile Yellow Capped Container


Transport And Storage

7 days (acidified) Ambient
8 days Refrigerated
30 days (acidified) Frozen (transport)


Collection Instructions

Record patients age on test request form and urine vial


Minimum Volume

1.5 mL Urine


Neonatal Volume

Clinical Interpretation

Reference Range:

Normetanephrine Random Urine: By Report ug/L
Metanephrine Random Urine: By Report ug/L
Creatinine, Random Urine: view ref range mg/dL
Normetanephrine/Creatinine Ratio: < 700 ug/g creat
Metanephrine/Creatinine Ratio: < 300 ug/g creat


Methodology:
  • Kinetic Alkaline Picrate
  • Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS)
Clinical Significance

Useful in the evaluation of pheochromocytoma


Production Schedule

Sites Performed
  • Quest - Chantilly
Days Performed
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Departments
  • Sendouts - Miscellaneous
Turn Around Time

2 to 3 days


Coding & Compliance

CDM

00913333


CPT Coding

82570, 83835