Patient Preparation:
If possible, patients should discontinue all drugs at least 1 week prior to collection. Medications that can interfere with the assay include: L-DOPA, Alpha-methyldopa (Aldomet), Buspirone, Codeine, Isoetharine, Isoproterenol, Mandelamine, Metoclopramide, Acetaminophen (high concentrations only), Labetalol, Catecholamine-containing drugs, MAO inhibitors, diuretics and vasodilators.
Specimen Requirements:
5.0 mL Random Urine in a Non-Sterile Yellow Capped Container
Collection Instructions:
Record patients age on test request form and urine vial
Minimum Volume:
1.5 mL Urine
Transport & Storage: Temperature/Stability:
7 days (acidified) Ambient
8 days Refrigerated
30 days (acidified) Frozen (transport)
Rejection Criteria:
pH > 3.0 and received unfrozen
Reference Range:
Normetanephrine Random Urine: By Report ug/L
Metanephrine Random Urine: By Report ug/L
Creatinine, Random Urine: view ref range mg/dL
Normetanephrine/Creatinine Ratio: < 700 ug/g creat
Metanephrine/Creatinine Ratio: < 300 ug/g creat
Methodology:
Kinetic Alkaline Picrate • Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
Clinical Significance:
Useful in the evaluation of pheochromocytoma
Custom Panel:
No
PRODUCTION SCHEDULE
Turn Around Time:
2 to 3 days
Days Performed:
Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed:
Quest - Valencia
PHL Test Code:
MSOT
EPIC Test Code:
Send Out Test Code:
3315UR
Alternate Test Names:
Metanephrines, Fractionated Urine Random
Included Tests:
Creatinine; Metanephrines; Normetanephrines; Total Metanephrines;
CPT Coding:
82570, 83835