Metanephrines, Fractionated Urine

Last Modified: 11/2/2018 5:51:01 AM

Patient Preparation: If possible, patients should discontinue all drugs at least 1 week prior to collection. Medications that can interfere with the assay include: L-DOPA, Alpha-methyldopa (Aldomet), Buspirone, Codeine, Isoetharine, Isoproterenol, Mandelamine, Metoclopramide, Acetaminophen (high concentrations only), Labetalol, Catecholamine-containing drugs, MAO inhibitors, diuretics and vasodilators.
Specimen Requirements: 5.0 mL Random Urine in a  Non-Sterile Yellow Capped Container
Collection Instructions:

Record patients age on test request form and urine vial

Minimum Volume: 1.5 mL Urine
Transport & Storage: Temperature/Stability: 7 days (acidified) Ambient
8 days Refrigerated
30 days (acidified) Frozen (transport)

Rejection Criteria: pH > 3.0 and received unfrozen
Reference Range: Normetanephrine Random Urine: By Report ug/L
Metanephrine Random Urine: By Report ug/L
Creatinine, Random Urine: view ref range mg/dL
Normetanephrine/Creatinine Ratio: < 700 ug/g creat
Metanephrine/Creatinine Ratio: < 300 ug/g creat
Methodology: Kinetic Alkaline Picrate • Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
Clinical Significance: Useful in the evaluation of pheochromocytoma
Custom Panel: No


Turn Around Time: 2 to 3 days
Days Performed: Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed: Quest - Valencia
PHL Test Code: MSOT
EPIC Test Code:
Send Out Test Code: 3315UR
Alternate Test Names: Metanephrines, Fractionated Urine Random
Included Tests: Creatinine; Metanephrines; Normetanephrines; Total Metanephrines; 
CPT Coding: 82570, 83835

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