Cryoglobulin (% Cryocrit)

Last Modified: 5/30/2019 10:03:37 AM


Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:

Overnight Fasting is Required

Specimen Requirements:

3.0 mL Serum from Red Top Tube(s) in a Plastic Vial from

Collection Instructions: Red Top after drawn must be full with 6 mL of fasting whole blood specimen in a red-top tube (no gel).

Allow sample to clot for one (1) hour in a 37°C Water bath, Oven, Incubator, or Heat Block. If none of these are available, adjust tap water in a container to 37°C.
Place collection tube into container and monitor temperature throughout the clotting process. Add more 37°C water to container as needed to maintain temperature throughout entire process.
After clotting, centrifuge the specimen for 10 minutes at 3000 rpm utilizing one of the 3 options below: 

1) In a 37°C centrifuge; or
2) In a bench-top centrifuge placed in a warm room at 37°C; or
3) In a bench-top centrifuge that you have prewarmed by running it for 10 minutes at 2000 rpm prior to centrifuging the clotted specimen tube. 

Note: If the sample is not kept at 37°C during all processing steps, the cryoprecipitate if present can precipitate out of solution and be lost in the clot or during the centrifugation process and result in a false negative result.
Transport screw-capped vial at room temperature. 

After centrifuging, decant serum into a screw-capped vial.

No other tests can be added to the tube; cryocrit and cryoglobulin evaluation only
 
Minimum Volume: 2.0 mL Serum
Transport & Storage: Temperature/Stability: 72 hours Ambient after centrifugation process
Rejection Criteria: Gross hemolysis • Grossly Lipemic • icteric • Refrigerated • Frozen • Serum Separator Tube (SST®) • Gel
Reference Range: Cryoglobulin Qualitative: Negative
%Cryocrit: None Detected
Critical Ranges:  
Test Comments:  
Methodology: Visual inspection
Clinical Significance: The Cryocrit is primarily intended for following a patient with previously defined and quantitated Cryoglobulins. The Cryocrit may consist of Cryoglobulins, fibrin or mixtures of Cryoglobulins and fibrin.
Documentation:  
Custom Panel: No

PRODUCTION SCHEDULE

Turn Around Time: 4 to 5 days
Days Performed: Sunday, Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed: Quest - Chantilly
PHL Test Code: CRYQ
EPIC Test Code: LAB2778
Send Out Test Code: 36562
Alternate Test Names: Cryoglobulin, Qualitative Reflex to %Cryocrit; Cryoglobulin, Quantitative
Included Tests:  
CPT Coding: 82595

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