EGFR Mutation Analysis

Last Modified: 3/3/2020 1:45:08 PM


Specimen Requirements:

FFPE tissue: Paraffin block
Collection Instructions: Alternatively, send 1 H&E slide plus 5-10 unstained slides cut at 5 or more microns. Please use positively-charged slides and 10% NBF fixative. Do not use zinc fixatives.
Transport & Storage: Temperature/Stability:  Refrigerate, and use cold pack for transport, cold pack should not be in direct contact with specimen.
Reference Range: Refer to Interpretive Results
Methodology: Molecular
Clinical Significance: EGFR mutation analysis is recommended in non-small cell lung carcinoma (NSCLC) to detect mutations (commonly L858R and exon 19 deletions) associated with increased sensitivity to EGFR tyrosine kinase inhibitors. Detection of TKI resistance mutations such as T790M in patients being treated with a TKI is useful for planning alternate treatment
Custom Panel: No

PRODUCTION SCHEDULE

Turn Around Time: 7 to 8 days
Sites Performed: NeoGenomics
PHL Test Code: PS
EPIC Test Code: N/A
Send Out Test Code: Soft Path - EGFRM
Alternate Test Names: EGFR; Epidermal Growth Factor Receptor
CPT Coding: 81235

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