HLA - B27 Antigen

Last Modified: 2/23/2021 9:10:11 AM

Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:  
Specimen Requirements:

5.0 mL Whole Blood in a Green Top Tube - Na Heparin

Collection Instructions:  
Minimum Volume: 2.0 mL
Transport & Storage: Temperature/Stability:

7 days Ambient (preferred)
5 days Refrigerated

Rejection Criteria: Hemolysis; lithium heparin tube; clotted; frozen
Reference Range: Frequency of occurrence 
Caucasians: 6-8%
African Americans: 3-4%
Asians: 1%
Critical Ranges:  
Test Comments:  
Methodology: Flow Cytometry
Clinical Significance: HLA-B27 is found in 90% of patients with ankylosing spondylitis and 80% in Reiter's disease. Ankylosing spondylitis affects 1 in 1000 caucasians. Ankylosing spondylitis is 10 times more common among individuals with HLA-B27 compared to individuals without this antigen.
Custom Panel: No


Turn Around Time: 3 to 5 days
Days Performed: Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed: Quest - Chantilly
PHL Test Code: HLAB
EPIC Test Code: IMO427
Send Out Test Code: 528
Alternate Test Names: Ankylosing Spondylitis; HLA-B27
Included Tests:  
CPT Coding: 86812

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