Osmotic Fragility, RBC

Overview

  • EPIC Code:
  • LAB2639
  • Soft Test Code:
  • Send Out Test Code:
  • FRAG
Alternate Names
  • Fragility, Osmotic (RBC)
  • OSMF1
  • Osmotic Fragility, Erythorcytes
  • RBC Fragility, Erythrocytes
  • Red Cell Fragility

Specimen Collection & Preparation

Specimen Requirements

3.0 mL Whole Blood in a Lavender Top Tube - EDTA  from the patient
and
3.0 mL Whole Blood in a Lavender Top Tube - EDTA  from a control


Transport And Storage

Refrigerate


Collection Instructions

Specimens may only be collected Monday through Thursday

1. Patient: Draw 3.0 mL of EDTA whole blood in a Lavender tube, refrigerate and label per PHL labeling requirements

2. Control: Draw 3.0 mL of EDTA whole blood in a Lavender tube from a normal, unrelated, non-smoking individual. Control sample must be drawn at the same time (or within 2 hours) of the patient. Label clearly on outermost label as: normal control and indicate gender of the control person on the tube.

3. Send both samples to the Send Out Department.

Order must include the patient's date of birth


Minimum Volume


Neonatal Volume

Clinical Interpretation

Reference Range:

0.50 g/dL NaCl (unincubated)
     Males: 0.0% - 47.8% hemolysis
     Females: 0.0% - 31.1% hemolysis
0.60 g/dL NaCl (incubated)
     Males: 18.7% - 67.4% hemolysis
     Females: 10.9% - 65.5% hemolysis
0.65 g/dL NaCl (incubated)
     Males: 4.4% - 36.6% hemolysis
     Females: 0.2% - 39.3% hemolysis
0.75 g/dL NaCl (incubated)
     Males: 0.8% - 9.1% hemolysis
     Females: 0.0% - 10.9% hemolysis


Methodology:
  • Osomotic lysis

Production Schedule

Sites Performed
  • Mayo Laboratory
Days Performed
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Departments
  • Sendouts - Clinical
Turn Around Time

4 to 6 days


Coding & Compliance

CDM

00918948


CPT Coding

85557