Neuron Specific Enolase

Last Modified: 9/15/2022 12:31:09 PM


Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:  
Specimen Requirements:

1.0 mL Serum in a SST Gold Top Tube
Collection Instructions:  
Minimum Volume: 0.3 mL
Transport & Storage: Temperature/Stability: 7 days Ambient
7 days Refrigerated
30 days Frozen
Reference Range: < or = 14 ng/mL
Critical Ranges:  
Test Comments:  
Methodology: EIA
Clinical Significance: Elevated levels of serum NSE are reported in patients with small cell carcinomas primarily of lung origin. Patients with neuroblastomas may also have high levels of NSE. Serum NSE can be used to monitor recurrence or progression of tumor in these cancer patients. Daily serial monitoring of serum NSE may also be used in comatose patients to assess neuronal damage. High NSE levels in comatose patients at 24hr and 48hr post cardio-pulmonary resusitation have been associated with poor outcome. Hemolysis can cause false positive results
Documentation:  
Custom Panel: No

PRODUCTION SCHEDULE

Turn Around Time: 3 to 5 days
Days Performed: Thursday
Sites Performed: Quest - Chantilly
PHL Test Code: ENOL1
EPIC Test Code: LAB2574
Send Out Test Code: 34476
Alternate Test Names: Neuron Specific Enolase (NSE), Serum; Neuron-Spec Enolase
Included Tests:  
CPT Coding: 86316

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