Hepatitis E Antibodies IgG, IgM

Overview

  • EPIC Code:
  • MISC
  • Soft Test Code:
  • MSOT
  • Send Out Test Code:
  • 15085
Alternate Names
  • Hep E Ab IgG, IgM
  • Hepatitis E Abs
  • Hepatitis E Antibodies
Clinical Significance

Hepatitis E virus (HEV) is the major etiologic agent of enterically transmiited non-A, non-B hepatitis worldwide and has a high case-fatality rate in pregnant women. Both IgM and IgG antibody to HEV (anti-HEV) are produced following infection. The titer of IgM anti-HEV declines rapidly during early convalescence; IgG anti-HEV persists and appears to provide at least short-term protection against disease.


Specimen Collection & Preparation

Specimen Requirements

1.0 mL Serum from a Red Top Tube in a Plastic Vial


Transport And Storage

7 days Ambient
14 days Refrigerated
30 days Frozen


Collection Instructions

 


Minimum Volume

0.2 mL Serum


Neonatal Volume

Clinical Interpretation

Reference Range:

Not detected

Hepatitis E Virus (HEV) is a major cause of enteric non-A hepatitis worldwide. Both HEV IgM and IgG are typically detected within one month after infection; IgM persists for about two months, whereas IgG levels persist for months to years after recovery. Approximately 20% of the U.S. population is positive for HEV IgG, indicating that HEV exposure is more common than previously thought.


Methodology:
  • Enzyme Linked Immunosorbent Immunoassay (ELISA)
Clinical Significance

Hepatitis E virus (HEV) is the major etiologic agent of enterically transmiited non-A, non-B hepatitis worldwide and has a high case-fatality rate in pregnant women. Both IgM and IgG antibody to HEV (anti-HEV) are produced following infection. The titer of IgM anti-HEV declines rapidly during early convalescence; IgG anti-HEV persists and appears to provide at least short-term protection against disease.


Production Schedule

Sites Performed
  • Quest - Chantilly to San Juan Capistrano
Days Performed
Tuesday
Friday
Departments
  • Sendouts - Miscellaneous
Turn Around Time

3 to 6 days


Coding & Compliance

CDM

00913333


CPT Coding

86790 x 2