Lyme Disease IgG & IgM, Confirmation

Last Modified: 5/17/2019 2:22:57 PM


Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:  
Specimen Requirements: 1.0 mL Serum from a Red Top Tube in a Plastic Vial
Collection Instructions:  
Minimum Volume: 0.25 mL
Transport & Storage: Temperature/Stability: 4 days Ambient
7 days Refrigerated (Preferred)
30 days Frozen
Rejection Criteria: Gross Hemolysis
Reference Range: B. burgdorferi IgG Ab: Negative
B. burgdorferi IgM Ab: Negative

Critical Ranges:  
Test Comments: Please note: The following comment will appear on the report when IgG is NEG and IgM is POS. Caution must be used in supporting a diagnosis of B. burgdorferi infection, when sera are Western blot IgM positive and Western blot IgG negative after the initial 4-week period from onset. Because the likelihood of a false-positive test result is high for these individuals, a positive IgM test alone is not recommended for use in determining active disease in persons with illness of longer than one
month's duration. 

IgG Western Blots which have 5 (or more) of the 10 significant bands are considered positive for specific antibody to B. burgdorferi. (Proceedings of the Second Conference of Lyme Disease, Dearborn, Michigan, 1994.) 

IgM Western Blot strips which have 2 (or more) of the 3 significant bands are considered positive for specific antibody to B. burgdorferi. (Proceedings of the Second Conference of Lyme Disease, Dearborn, Michican, 1994.)
Methodology: Western Blot
Clinical Significance: Lyme disease is transmitted by a tick vector carrying Borrelia burgdorferi. Immunoblot testing qualitatively examins, with high specificity, antibodies in a patient's specimen. Immunoblot testing is appropriate for confirming a detected EIA or IFA test result.
Documentation:  
Custom Panel: No

PRODUCTION SCHEDULE

Turn Around Time: 3 to 5 days
Days Performed: Monday, Wednesday, Friday
Sites Performed: Quest - Chantilly
PHL Test Code: LYMQ
EPIC Test Code: LAB2539
Send Out Test Code: 8593
Alternate Test Names: B. Burgdoeferi RI Ab; B. burgdorferi IgG and IgM; Borrelia Burgdorferi IgG and IgM; Lyme AB IgG, IgM; Lyme Confirmation; Lyme Disease Antibodies IgG & IgM by Western Blot; Lyme Disease Antibodies IgG & IgM, Confirmation; Lymes
Included Tests:  
CPT Coding: 86617 x 2

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