Hemoglobin A2, Quantitative

Overview

  • EPIC Code:
  • Soft Test Code:
  • MSOT
  • Send Out Test Code:
  • 4974
Alternate Names
  • A2 Column
Clinical Significance

Screen for beta thalassemia. Note that iron deficiency can result in decreased Hb-A2 levels and, therefore, may lead to a normal Hb-A2 level even in affected patients


Specimen Collection & Preparation

Patient Preparation

Blood transfusion within the last 4 months may affect results


Specimen Requirements

5.0 mL Whole Blood in a Lavender Top Tube - EDTA


Transport And Storage

7 days Ambient (transport
7 days Refrigerated


Collection Instructions

Patient age and ethnicity must be on order for proper interpretation.


Minimum Volume

2.0 mL Whole Blood


Neonatal Volume

Clinical Interpretation

Reference Range:

< 31 days: < 1.0 %
< 91 days: < 2.3 %
< 181 days: < 2.5 %
< 366 days: < 2.7 %
>= 366 days: 1.8 - 3.5 %


Methodology:
  • High Performance Liquid Chromatography (HPLC)
Clinical Significance

Screen for beta thalassemia. Note that iron deficiency can result in decreased Hb-A2 levels and, therefore, may lead to a normal Hb-A2 level even in affected patients


Production Schedule

Sites Performed
  • Quest - Chantilly
Days Performed
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Departments
  • Sendouts - Miscellaneous
Turn Around Time

2 to 3 days


Coding & Compliance

CDM

00913333


CPT Coding

83020