Aldosterone, LC/MS/MS

Last Modified: 10/20/2021 12:32:29 PM

Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:  
Specimen Requirements:

1.0 mL Plasma from a Lavender Top Tube - EDTA in a Plastic Vial

Collection Instructions: Separate serum after clotting. 

Draw Upright Specimens at least 1/2 hour after patient sits up
Minimum Volume: 0.25 mL Serum
Transport & Storage: Temperature/Stability:

4 days Ambient
7 days Refrigerated
28 days Frozen

Rejection Criteria: Collected in Serum Separator Tube (SST)
Reference Range: Refer to Interpretive Results


Critical Ranges:  
Test Comments:  
Methodology: Chromatography / Mass Spectrometry
Clinical Significance: Approximately 1-2% of individuals with primary hypertension have primary hyperaldosteronism characterized by hypokalemia (low potassium) and low direct renin. Because serum aldosterone concentrations vary due to dietary sodium intake and body position, some physicians prefer measurement of 24-hour urine concentrations for aldosterone.
Documentation: *Pediatric data from J Clin Endocrinol Metab. 1992;
75:1491 and J CLin Endocrinol Metab. 1989; 69:1133-1136.
Custom Panel: No


Turn Around Time: 3 to 6 days
Days Performed: Monday, Tuesday, Wednesday, Thursday, Friday
Sites Performed: Quest - Chantilly
PHL Test Code: ALDOS
EPIC Test Code: LAB557
Send Out Test Code: 17181
Included Tests:  
CPT Coding: 82088

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