Lysozyme

Overview

  • EPIC Code:
  • LAB3301
  • Soft Test Code:
  • LYSOZ
  • Send Out Test Code:
  • 619
Alternate Names
  • Muramidase
Clinical Significance

Lysozyme in the serum is primarily due to the degradation of granulocytes and monocytes and its concentration reflects the turnover of these cells. Increases are seen in benign and malignant processes. Serum lysozyme is elevated in patients with acute or chronic granulocytic or monocytic leukemias and levels decrease with successful treatment. Conversely, patients with lymphocytic leukemia may have depressed plasma lysozyme levels.


Specimen Collection & Preparation

Specimen Requirements

1.0 mL Serum in a SST Gold Top Tube in a Plastic Vial


Transport And Storage

24 hours Ambient
15 days Refrigerated (Transport)
18 days Frozen  


Collection Instructions

Centrifuge serum specimens within 1 hour of collection. 
Transfer serum to sterile, plastic, screw-capped vial(s). 
Freeze and ship frozen samples on dry ice.

Delayed separation of the serum can result in spuriously high levesl of lysozyme, presumably because of the breakdown of leukocytes.


Minimum Volume

0.5 mL Serum


Neonatal Volume

Clinical Interpretation

Reference Range:

5.0-11.0 mcg/mL


Methodology:
  • Enzymatic
Clinical Significance

Lysozyme in the serum is primarily due to the degradation of granulocytes and monocytes and its concentration reflects the turnover of these cells. Increases are seen in benign and malignant processes. Serum lysozyme is elevated in patients with acute or chronic granulocytic or monocytic leukemias and levels decrease with successful treatment. Conversely, patients with lymphocytic leukemia may have depressed plasma lysozyme levels.


Production Schedule

Sites Performed
  • Quest - Chantilly
Days Performed
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Departments
  • Sendouts - Miscellaneous
Turn Around Time

1 to 2 days


Coding & Compliance

CDM

'00910032


CPT Coding

85549