Lysozyme in the serum is primarily due to the degradation of granulocytes and monocytes and its concentration reflects the turnover of these cells. Increases are seen in benign and malignant processes. Serum lysozyme is elevated in patients with acute or chronic granulocytic or monocytic leukemias and levels decrease with successful treatment. Conversely, patients with lymphocytic leukemia may have depressed plasma lysozyme levels.
1.0 mL Serum in a SST Gold Top Tube in a Plastic Vial
24 hours Ambient
15 days Refrigerated (Transport)
18 days Frozen
Centrifuge serum specimens within 1 hour of collection.
Transfer serum to sterile, plastic, screw-capped vial(s).
Freeze and ship frozen samples on dry ice.
Delayed separation of the serum can result in spuriously high levesl of lysozyme, presumably because of the breakdown of leukocytes.
0.5 mL Serum
5.0-11.0 mcg/mL
Lysozyme in the serum is primarily due to the degradation of granulocytes and monocytes and its concentration reflects the turnover of these cells. Increases are seen in benign and malignant processes. Serum lysozyme is elevated in patients with acute or chronic granulocytic or monocytic leukemias and levels decrease with successful treatment. Conversely, patients with lymphocytic leukemia may have depressed plasma lysozyme levels.
1 to 2 days
'00910032
85549