Last Modified:
4/12/2023 7:48:18 AM
Medical Necessity Documentation:
Client Notes:
Patient Preparation:
Specimen Requirements:
1.0 mL Serum in a SST Gold Top Tube in a Plastic Vial
Collection Instructions:
Centrifuge serum specimens within 1 hour of collection.
Transfer serum to sterile, plastic, screw-capped vial(s).
Freeze and ship frozen samples on dry ice.
Delayed separation of the serum can result in spuriously high levesl of lysozyme, presumably because of the breakdown of leukocytes.
Minimum Volume:
0.5 mL Serum
Transport & Storage: Temperature/Stability:
24 hours Ambient
15 days Refrigerated (Transport)
18 days Frozen
Rejection Criteria:
Room temperature samples older than 24 hours • Plasma collected in citrate or heparin • Moderate to gross hemolysis • Grossly lipemic
Reference Range:
5.0-11.0 mcg/mL
Critical Ranges:
Test Comments:
Methodology:
Enzymatic
Clinical Significance:
Lysozyme in the serum is primarily due to the degradation of granulocytes and monocytes and its concentration reflects the turnover of these cells. Increases are seen in benign and malignant processes. Serum lysozyme is elevated in patients with acute or chronic granulocytic or monocytic leukemias and levels decrease with successful treatment. Conversely, patients with lymphocytic leukemia may have depressed plasma lysozyme levels.
Documentation:
Custom Panel:
No
PRODUCTION SCHEDULE
Turn Around Time:
1 to 2 days
Days Performed:
Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed:
Quest - Chantilly
PHL Test Code:
LYSOZ
EPIC Test Code:
LAB3301
Send Out Test Code:
619
Alternate Test Names:
Muramidase
Included Tests:
CPT Coding:
85549
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