17-Hydroxyprogesterone

Last Modified: 12/11/2018 10:10:16 AM


Specimen Requirements: 0.5 mL Serum from a Red Top Tube in a Plastic Vial
Collection Instructions: Separate serum after clotting. Ship serum refrigerated or frozen
Minimum Volume: 0.25 mL Serum
Transport & Storage: Temperature/Stability: 48 hours Ambient
7 days Refrigerated (Transport)
2 years Frozen
Rejection Criteria: Serum Separator Tube (SST®) • Do not submit glass tubes
Reference Range:
Adult Male    
18-30 Years 32-307 ng/dL
31-40 Years 42-196 ng/dL
41-50 Years 33-195 ng/dL
51-60 Years 37-129 ng/dL
Adult Female    
Follicular Phase ≤185 ng/dL
Luteal Phase ≤285 ng/dL
Postmenopausal ≤45 ng/dL
Pregnancy    
  First Trimester 78-457 ng/dL
  Second Trimester 90-357 ng/dL
  Third Trimester 144-578 ng/dL
Pediatric    
1-12 Months 11-170 ng/dL
1-4 Years 4-115 ng/dL
5-9 Years ≤90 ng/dL
10-13 Years ≤169 ng/dL
14-17 Years 16-283 ng/dL
Infant    
Premature (31-35 Weeks) ≤360 ng/dL
Term (3 Days) ≤420 ng/dL
Tanner Stages    
II-III Male 12-130 ng/dL
II-III Female 18-220 ng/dL
IV-V Male 51-190 ng/dL
IV-V Female 36-200 ng/dL
Methodology: Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
Clinical Significance: 17-Hydroxyprogesterone is elevated in patients with Congenital Adrenal Hyperplasia (CAH). CAH is a group of autosomal recessive diseases characterized by a deficiency of cortisol and an excess of ACTH concentration. 17-Hydroxyprogesterone is also useful in monitoring cortisol replacement therapy and in evaluating infertility and adrenal and ovarian neoplasms.
Custom Panel: No

PRODUCTION SCHEDULE

Turn Around Time: 2 to 5 days
Days Performed: Sunday, Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed: Quest - Chantilly
PHL Test Code: 17PRO
EPIC Test Code: LAB720
Send Out Test Code: 17180
Alternate Test Names: 17-OHProgesterone
CPT Coding: 83498

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