Last Modified:
11/18/2021 10:02:45 AM
Medical Necessity Documentation:
Client Notes:
Patient Preparation:
Specimen Requirements:
1.0 mL Serum from a Red Top Tube in a Plastic Vial
Collection Instructions:
For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotion supplementation.
For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Allow blood to clot at room temperature (20-26 degrees C)
Centrifuge immediately to separate the serum from the cells.
Freeze as soon as possible.
Minimum Volume:
0.5 mL
Transport & Storage: Temperature/Stability:
21 days Frozen
Rejection Criteria:
Hemolysis; heat inactivated specimens: patient administered with biotin within 8 hours; specimens stabilized with azide(SST GEL); SST
Reference Range:
Osteocalcin, N-MID:
< 10 years: 47 - 142
< 14 years: 49 - 167
Male < 18 years: 26 - 203
Male >= 18 years: 9 - 38
Female < 18 years: 14 - 85
Female >= 18 years: 8 - 32 ng/mL
Critical Ranges:
Test Comments:
Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low
Methodology:
Electrochemiluminescence (ECLIA)
Clinical Significance:
Osteocalcin, the most abundant non-collagen protein in bone matrix, is a bone-specific, calcium binding protein. Serum osteocalcin levels are related to the rate of bone turnover in various disorders of bone metabolism, e.g., osteoporosis, primary and secondary hyperparathyroidism, and Paget's disease
Documentation:
Custom Panel:
No
PRODUCTION SCHEDULE
Turn Around Time:
1 to 4 days
Days Performed:
Tuesday, Thursday, Saturday
Sites Performed:
Quest - Chantilly
PHL Test Code:
OSTC
EPIC Test Code:
LAB1060
Send Out Test Code:
16322
Alternate Test Names:
Osteocalcin, N-mid
Included Tests:
CPT Coding:
83937
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