Fentanyl and Metabolite, Quantitative

Last Modified: 10/2/2017 4:00:26 PM

Specimen Requirements:

4.0 mL Serum from a Red Top Tube in a Plastic Vial

Collection Instructions:
Mix by inverting tube 8 times

Centrifuge to separate from cells ASAP or within 2 hours of collection.

Please indicate On Order:
1. Dose - List drug amount and include the units of measure
2. Route - List the route of administration (IV, oral, etc.)
3. Dose Frequency - Indicate how often the dose is administered (per day, per week, as needed, etc.)
4. Type of Draw - Indicate the type of blood draw (Peak, Trough, Random, etc.)
Minimum Volume: 2.0 mL
Transport & Storage: Temperature/Stability: 1 week Ambient
2 weeks Refrigerated
3 years Frozen

Avoid repeated freeze/thaw cycles
Rejection Criteria: Whole blood. Serum separator tubes, Light Blue (Sodium Citrate), or Plasma separator tubes. Specimens exposed to repeated freeze/thaw cycles.
Reference Range:
Fentanyl 0.1 ng/mL
Norfentanyl 0.1 ng/mL
Test Comments: For medical purposes only; not valid for forensic use.

The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, or limitations of testing. The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.

This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Methodology: Quantitative Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Custom Panel: No


Turn Around Time: 3 to 5 days
Days Performed: Tuesday, Thursday, Saturday
Sites Performed: South Bend Medical Foundation to ARUP Lab
PHL Test Code: MSOT
EPIC Test Code:
Send Out Test Code: 45853
Alternate Test Names: Actiq; Duragesic; Fentanyl and Norfentanyl; Fentora; Instanyl; Ionsys; Onsolis; Sublimaze
Included Tests: Fentanyl; Norfentanyl
CPT Coding: 80354

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