KRAS Mutation Analysis

Last Modified: 3/3/2020 3:16:05 PM


Specimen Requirements:

FFPE tissue: Paraffin block
Collection Instructions: Alternatively, send 1 H&E slide plus 5-10 unstained slides cut at 5 or more microns. Please use positively-charged slides and 10% NBF fixative. Do not use zinc fixatives.
Transport & Storage: Temperature/Stability:  Refrigerate, and use cold pack for transport, cold pack should not be in direct contact with specimen.
Reference Range: Refer to Interpretive Results
Methodology: Molecular
Clinical Significance:

Testing is recommended in colorectal cancer as mutations are associated with resistance and shorter overall survival with EGFR-antagonist therapies such as cetuximab or panitumumab. Testing in non-small cell lung cancer may provide prognostic information and predict poor response to EGFR tyrosine kinase inhibitors.
Custom Panel: No

PRODUCTION SCHEDULE

Turn Around Time: 7 to 8 days
Sites Performed: NeoGenomics
PHL Test Code: PS
EPIC Test Code: N/A
Send Out Test Code: Soft Path - KRAS2 & KRASV
Alternate Test Names: KRAS Mutation Testing
CPT Coding: 81275, 81276

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