CD20 by Flow Cytometry, Miscellaneous

Overview

  • EPIC Code:
  • MISC
  • Soft Test Code:
  • Send Out Test Code:
  • 10981
Alternate Names
  • CD 20
  • CD 20, Flow Cytometry
  • Rituxan Sensitivity
Clinical Significance

CD20 antigen is expressed on the surface of >90% of B-cell Non-Hodgkin's Lymphomas (NHL). Binding to CD20 antigen is necessary for the antitumor effect of Rituxan.


Specimen Collection & Preparation

Test Notes

Prior to collecting the specimen, contact the Send Outs Department to verify that shipment to the testing laboratory can occur within the specimen's stability limits.


Specimen Overview

Whole blood or bone marrow

Specimen Requirements:

-AND-

5.0 ml sodium heparin (green-top) tube
Minimum Volume:
1.0 mL*

* This volume does not allow for repeat testing

Rejection Criteria:

Refrigerated samples

Frozen samples

Clotted samples


Transport and Storage:
  • Ambient (18-24°C): 72 hours

Clinical Interpretation

Reference Range:

Reference ranges are provided on report as general guidance only. 


Methodology:
  • Flow Cytometry (FC)
Clinical Significance

CD20 antigen is expressed on the surface of >90% of B-cell Non-Hodgkin's Lymphomas (NHL). Binding to CD20 antigen is necessary for the antitumor effect of Rituxan.


Documentation

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It is not cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.


Production Schedule

Days Performed
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Schedule Frequency
Quest- San Juan
Departments
  • Sendouts - Miscellaneous
Turn Around Time

48 to 72 hours


Coding & Compliance

CDM

01396586


CPT Coding

86356