Antiepidermal Antibodies with Reflex To Titers

Last Modified: 3/12/2018 9:16:40 AM


Specimen Requirements: 0.5 mL Serum from a Red Top Tube in a Plastic Vial
Minimum Volume: 0.1 mL serum
Transport & Storage: Temperature/Stability: 48 hours Abient
7 days Refrigerated
2 months Frozen
Rejection Criteria: Gross hemolysis • Grossly lipemic • Gross icterus
Reference Range: Skin Autoantibodies, Intercellular: 1:10 titer
Skin Autoantibodies, Dermal-Epidermal: 1:10 titer
Test Comments:

 If Intercellular Substance Antibody Screen is positive, then Intercellular Substance Antibody Titer will be performed at an additional charge (CPT code(s): 86256).
If Basement Membrane Zone Antibody Screen is positive, then Basement Membrane Zone Titer will be performed at an additional charge (CPT code(s): 86256).

Methodology: IFA
Clinical Significance: Skin antibodies (inter-epithelial) are found in 90% of patients with Pemphigus vulgaris and P. foliaceus. Dermal-epidermal skin antibodies are antibodies found in 90% of patients with Bullous pemphigoid and 90% of Cicatricial pemphigoid
Custom Panel: No

PRODUCTION SCHEDULE

Days Performed: Wednesday
Sites Performed: Quest - Valencia
PHL Test Code: MSOT
EPIC Test Code:
Send Out Test Code: 37097
Alternate Test Names: Pemphigoid AB (IFA); Skin Total ABS, Pemphigus & Pemphigoid; Skin Total Autoantibodies, Inter-Epithelial & Derm
Included Tests:  Basement Membrane Zone Antibody Screen ; Intercellular Substance Antibody Screen
CPT Coding: 86255 x 2

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