Mixing Study

Overview

  • EPIC Code:
  • LAB2444
  • Soft Test Code:
  • MIXS1
Alternate Names
  • Circulating Anticoagulant
  • Mixing Studies
Clinical Significance

A mixing study aids in differentiating the cause of a prolonged prothrombin time (PT) and/or prolonged activated partial thromboplastin time (APTT).


Specimen Collection & Preparation

Client Notes

Contact Client Response at 266-1500 (Option 2) for Stat Courier


Specimen Requirements

2.0 mL Platelet Poor Plasma from 2 Blue Top Tubes - 3.2% Na Citrate in a Plastic Vial


Transport And Storage

4 hours Ambient

Testing must be completed within 4 hours of collection

Should be at the testing laboratory Parkview Regional within 2 hours of collection.


Collection Instructions

Specimens must NOT collected from indwelling lines or ports.

Correct ratio of Blood to Citrate is critical (9:1). Specimens must be filled within +/- 10% of stated volume.

Order must include the patient's medication history at the time of specimen collection. 


Minimum Volume


Neonatal Volume

Clinical Interpretation

Reference Range:

Refer to Interpretive Pathology Report


Methodology:
  • Optical
Clinical Significance

A mixing study aids in differentiating the cause of a prolonged prothrombin time (PT) and/or prolonged activated partial thromboplastin time (APTT).


Documentation

PT & APTT will be performed at time of collection. If the prolongation of the PT & APTT is less than 2 seconds and 5 seconds over the respective reference ranges, the mixing study will not be performed per established criteria of Parkview Laboratories.


Production Schedule

Sites Performed
  • Parkview Regional Medical Center
Days Performed
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Departments
  • Coagulation
Turn Around Time

1 to 4 days


Coding & Compliance

CDM

01421001, 01421003, 01421000, 01450039, 01450046


CPT Coding

85732 x 2, 85611, 85610, 85730