Mixing Study

Last Modified: 6/17/2019 1:14:45 PM

Medical Necessity Documentation:  
Client Notes: Contact Client Response at 266-1500 (Option 2) for Stat Courier
Patient Preparation:  
Specimen Requirements: 2.0 mL Platelet Poor Plasma from 2 Blue Top Tubes - 3.2% Na Citrate in a Plastic Vial
Collection Instructions:
Specimens must NOT collected from indwelling lines or ports.

Correct ratio of Blood to Citrate is critical (9:1). Specimens must be filled within +/- 10% of stated volume.

Order must include the patient's medication history at the time of specimen collection. 
Transport & Storage: Temperature/Stability: 4 hours Ambient

Testing must be completed within 4 hours of collection

Should be at the testing laboratory Parkview Regional within 2 hours of collection.
Rejection Criteria: If heparin, low molecular weight heparin, direct thrombin inhibitor or warfarin are present. Mixing Study Medication Screen must be completed at the time of specimen collection; Recent anticoagulation therapy
Reference Range: Refer to Interpretive Pathology Report
Critical Ranges:  
Test Comments:  
Methodology: Optical
Clinical Significance: A mixing study aids in differentiating the cause of a prolonged prothrombin time (PT) and/or prolonged activated partial thromboplastin time (APTT).
Documentation: PT & APTT will be performed at time of collection. If the prolongation of the PT & APTT is less than 2 seconds and 5 seconds over the respective reference ranges, the mixing study will not be performed per established criteria of Parkview Laboratories.
Custom Panel: No


Turn Around Time: 1 to 4 days
Days Performed: Sunday, Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed: Parkview Regional Medical Center
PHL Test Code: MIXS1
EPIC Test Code: LAB2444
Alternate Test Names: Circulating Anticoagulant; Mixing Studies
Included Tests:  
CPT Coding: 85732 x 2, 85611, 85610, 85730

Go back to the top of the page.