A mixing study aids in differentiating the cause of a prolonged prothrombin time (PT) and/or prolonged activated partial thromboplastin time (APTT).
Contact Client Response at 266-1500 (Option 2) for Stat Courier
* This volume does not allow for repeat testing
Specimens must NOT be collected from indwelling lines or ports.
Correct ratio of Blood to Citrate is critical (9:1). Specimens must be filled within +/- 10% of stated volume.
Mixing Study Medication Screen must be completed at the time of specimen collection.
Clotted samples
Improperly filled tubes (under or overfilled)
Wrong anticoagulant (3.8% sodium citrate is NOT acceptable)
Patients with hematocrit (HCT) >55% (red cell volume is >1/2 tube volume)
Hemolyzed samples
Whole blood samples received on ice or refrigerated
Improperly labeled specimens
If heparin, low molecular weight heparin, direct thrombin inhibitor or warfarin are present
Specimens stored at room temperature must have all mixing study testing completed within 4 hours of collection.
If testing cannot be performed immediately, platelet poor plasma may be frozen at -20°C or colder within 2 hours of collection.
Do not freeze in frost-free freezer.
The preferred specimen is whole blood specimen stored at room temperature and received at the testing site (PRMC) within 2 hours of collection.
Refer to Interpretive Pathology Report
A mixing study aids in differentiating the cause of a prolonged prothrombin time (PT) and/or prolonged activated partial thromboplastin time (APTT).
PT and APTT will be performed at time of collection. If the prolongation of the PT and APTT is less than 2 seconds and 5 seconds over the respective reference ranges, the mixing study will not be performed per established criteria of Parkview Laboratories.
1 to 4 days
01421001, 01421003, 01421000, 01450039, 01450046
85732 x 2, 85611, 85610, 85730