Oncology Chromosome Analysis- BM/PB

Clinical Significance

Cytogenetic analysis used to determine chromosomal abnormalities important in diagnosis of hematologic malignancies, disease monitoring, and response to certain treatments

Client Notes

Order must include the reason for testing and a current CBC report and a stained peripheral blood slide

Patient Preparation

Anti-leukemic drug therapy may suppress cell division. The patient should not have received these drugs within 6 weeks of sample collection.

Specimen Requirements

3.0 mL Bone Marrow in a Green Top Tube - Na Heparin 

Transport And Storage

Ambient (Transport)

Specimen viability decreases during transit. Send specimen to testing laboratory for viability determination.

Collection Instructions

Bone Marrow must contain 10% less mature myelocytes, pros or blasts

Clinical history/reason for referral is required with test order. Previous bone marrow transplant or therapy information, if applicable, should be provided with test order.

Minimum Volume

2.0 mL Bone Marrow

Neonatal Volume

Infants: 2-3 mL (pediatric 3mL vacutainer)

Reference Range:

Reference Range Not Established

Methodology:

• Chromosome Analysis

Clinical Significance

Cytogenetic analysis used to determine chromosomal abnormalities important in diagnosis of hematologic malignancies, disease monitoring, and response to certain treatments

CDM

00918614; 00918615

CPT Coding

88237, 88262, 88291