Factor XIII, Functional

Overview

  • EPIC Code:
  • Soft Test Code:
  • MSOT
  • Send Out Test Code:
  • 14461
Alternate Names
  • Factor Testing
Clinical Significance

Low Factor XIII levels, i.e., <15%, may cause a bleeding disorder and levels <2% have been associated with spontaneous introcranial hemorrhage


Specimen Collection & Preparation

Specimen Requirements

1.0 mL Platelet Poor Plasma from a Blue Top Tube - 3.2% Na Citrate in a Plastic Vial


Transport And Storage

24 hours Ambient
24 hours Ambient
14 days Frozen


Collection Instructions

Platelet poor plasma: 
Centrifuge light blue-top tube 15 minutes at approximately 1500 x g within 60 minutes of collection. 
Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. 
Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. 
Plasma must be free of platelets (< 10,000/mcL). 
Freeze immediately and ship on dry ice. 

Note oral anticoagulant therapy on order


Minimum Volume

0.3 mL Platelet Poor Plasma


Neonatal Volume

Clinical Interpretation

Reference Range:

57-192 % activity


Methodology:
  • Chromogenic
Clinical Significance

Low Factor XIII levels, i.e., <15%, may cause a bleeding disorder and levels <2% have been associated with spontaneous introcranial hemorrhage


Documentation

Research Use Only
This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.


Production Schedule

Sites Performed
  • Quest - Chantilly to San Juan Capistrano
Days Performed
Thursday
Departments
  • Sendouts - Miscellaneous
Turn Around Time

2 to 3 days


Coding & Compliance

CDM

00913333


CPT Coding

85290