Mannan-Binding Lectin Pathway Function Test (C4b)

Overview

  • EPIC Code:
  • LAB2718
  • Soft Test Code:
  • MSOT
  • Send Out Test Code:
  • 39788
Alternate Names
  • Mannan Binding
  • Mannose Binding Lec
  • Mannose-Binding Lectin
  • MBL
  • MBL Test
Clinical Significance

Deficiency in either MBL or MASP-2 appears to predispose individuals to serious infections (e.g. pneumonitis, sepsis, osteomyelitis, gastroenteritis and meningitis) especially during childhood before the adaptive immunity has fully developed.


Specimen Collection & Preparation

Specimen Requirements:

-OR-

2.0 mL Serum from a Red Top Tube in a Plastic Vial
Minimum Volume:
0.1 mL Serum*

* This volume does not allow for repeat testing

Transport and Storage:
  • Ambient: 7 Days
  • Refrigerated: 28 Days
  • Frozen (-20 C or colder): 1 Year

Clinical Interpretation

Reference Range:

>200 ng/mL


Methodology:
  • Enzyme Immunoassay (EIA)
Clinical Significance

Deficiency in either MBL or MASP-2 appears to predispose individuals to serious infections (e.g. pneumonitis, sepsis, osteomyelitis, gastroenteritis and meningitis) especially during childhood before the adaptive immunity has fully developed.


Production Schedule

Sites Performed
  • Quest Chantilly to Eurofins
Days Performed
Monday
Tuesday
Wednesday
Thursday
Friday
Departments
  • Sendouts - Clinical
Turn Around Time

5 to 7 days


Coding & Compliance

CDM

00910623


CPT Coding

86161


Medical Necessity May Apply
Medical Necessity Documentation

Can Not be billed to Medicare or Medicaid Must have ABN