Mannan-Binding Lectin Pathway Function Test (C4b)

Last Modified: 1/15/2024 12:45:33 PM


  Medicare Medical Necessity Restrictions May Apply
Medical Necessity Documentation: Must have ABN - Can Not be billed to Medicare or Medicaid 
Client Notes:  
Patient Preparation: Overnight fasting is preferred
Specimen Requirements: 2.0 mL Serum from a Red Top Tube in a Plastic Vial
Collection Instructions: Do not submit specimens that have been heat treated. Do not submit the sample in a glass tube.

Do not collect in a Serum Separator Tube (SST or PST)
Minimum Volume: 0.1 mL Serum
Transport & Storage: Temperature/Stability:

7 days Ambient 
28 days Refrigerated
1 year Frozen

Reference Range: >200 ng/mL
Critical Ranges:  
Test Comments:  
Methodology: Enzyme Immunoassay
Clinical Significance: Deficiency in either MBL or MASP-2 appears to predispose individuals to serious infections (e.g. pneumonitis, sepsis, osteomyelitis, gastroenteritis and meningitis) especially during childhood before the adaptive immunity has fully developed
Documentation:
Custom Panel: No

PRODUCTION SCHEDULE

Turn Around Time: 5 to 7 days
Days Performed: Monday, Tuesday, Wednesday, Thursday, Friday
Sites Performed: Quest - Chantilly to Europhins
PHL Test Code: MBL
EPIC Test Code: LAB2718
Send Out Test Code: 39788
Alternate Test Names: Mannan Binding ; Mannose Binding Lec; Mannose-binding Lectin; MBL
Included Tests:  
CPT Coding: 86161

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