Alkaline Phosphatase, Bone Specific

Last Modified: 2/4/2019 4:25:12 PM


Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:  
Specimen Requirements:

1.0 mL Serum from a SST Gold Top Tube
Collection Instructions: Allow serum samples to clot completely before centrifugation
Minimum Volume: 0.3 mL Serum
Transport & Storage: Temperature/Stability: 7 days Ambient
7 days Refrigerated
60 days Frozen
Rejection Criteria: Gross hemolysis • Gross lipemia • Non-serum samples • Grossly icteric
Reference Range:
Adult Male  
18-29 Years 8.4-29.3 mcg/L
30-39 Years 7.7-21.3 mcg/L
40-49 Years 7.0-18.3 mcg/L
50-68 Years 7.6-14.9 mcg/L
Adult Female  
18-29 Years 4.7-17.8 mcg/L
30-39 Years 5.3-19.5 mcg/L
40-49 Years 5.0-18.8 mcg/L
50-76 Years 5.6-29.0 mcg/L
Premenopausal  
35-45 Years 5.0-18.2 mcg/L
Pediatric Male (mcg/mL) Female (mcg/mL)
2-24 months* 25.4-124.0 25.4-124.0
25 months-5 Years Not established Not established
6-9 Years 41.0-134.6 41.0-134.6
10-13 Years 43.8-177.4 24.2-154.2
14-17 Years 13.7-128.0 10.5-75.2
*Pediatric data from Int J Biol Markers 1996; 11:159-164.
Critical Ranges:  
Test Comments:  
Methodology: Immunoenzymatic
Clinical Significance: The Bone-Specific Alkaline Phosphatase (BSAP) assay provides a general index of bone formation and a specific index of total osteoblast activity. BSAP and osteocalcin are the most effective markers of bone formation and are particularly useful for monitoring bone formation therapies and antiresorptive therapies.
Documentation:  
Custom Panel: No

PRODUCTION SCHEDULE

Turn Around Time: 1 to 2 days
Days Performed: Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed: Quest - Chantilly
PHL Test Code: APBS
EPIC Test Code: LAB2939
Send Out Test Code: 29498
Alternate Test Names: Bone-Specific Alkaline Phosphatase ; BSAP
Included Tests:  
CPT Coding: 84075

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