Alkaline Phosphatase, Bone Specific

Last Modified: 2/4/2019 4:25:12 PM

Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:  
Specimen Requirements:

1.0 mL Serum from a SST Gold Top Tube

Collection Instructions: Allow serum samples to clot completely before centrifugation
Minimum Volume: 0.3 mL Serum
Transport & Storage: Temperature/Stability: 7 days Ambient
7 days Refrigerated
60 days Frozen
Rejection Criteria: Gross hemolysis • Gross lipemia • Non-serum samples • Grossly icteric
Reference Range:
Adult Male  
18-29 Years 8.4-29.3 mcg/L
30-39 Years 7.7-21.3 mcg/L
40-49 Years 7.0-18.3 mcg/L
50-68 Years 7.6-14.9 mcg/L
Adult Female  
18-29 Years 4.7-17.8 mcg/L
30-39 Years 5.3-19.5 mcg/L
40-49 Years 5.0-18.8 mcg/L
50-76 Years 5.6-29.0 mcg/L
35-45 Years 5.0-18.2 mcg/L
Pediatric Male (mcg/mL) Female (mcg/mL)
2-24 months* 25.4-124.0 25.4-124.0
25 months-5 Years Not established Not established
6-9 Years 41.0-134.6 41.0-134.6
10-13 Years 43.8-177.4 24.2-154.2
14-17 Years 13.7-128.0 10.5-75.2
*Pediatric data from Int J Biol Markers 1996; 11:159-164.
Critical Ranges:  
Test Comments:  
Methodology: Immunoenzymatic
Clinical Significance: The Bone-Specific Alkaline Phosphatase (BSAP) assay provides a general index of bone formation and a specific index of total osteoblast activity. BSAP and osteocalcin are the most effective markers of bone formation and are particularly useful for monitoring bone formation therapies and antiresorptive therapies.
Custom Panel: No


Turn Around Time: 1 to 2 days
Days Performed: Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed: Quest - Chantilly
PHL Test Code: APBS
EPIC Test Code: LAB2939
Send Out Test Code: 29498
Alternate Test Names: Bone-Specific Alkaline Phosphatase ; BSAP
Included Tests:  
CPT Coding: 84075

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