Herpes Select 1 & 2 IgG Antibodies

Last Modified: 3/27/2019 4:02:32 PM

Medical Necessity Documentation:
Duplicate testing on this test is not acceptable per Medicare:  Testing to only be done every 365 days
Client Notes:  
Patient Preparation:  
Specimen Requirements: 1.0 mL Serum in a SST Gold Top Tube
Collection Instructions:  
Transport & Storage: Temperature/Stability:
48 hours Refrigerated
30 days Frozen

Specimen to be transported Refrigerated to PRMC within 48 hours of collection to be frozen by Immunology department to maintain specimen integrity until testing occurs. Do not transport Frozen.
Reference Range:
OD ratio < 0.90 indicates no detectable HSV IgG antibody. Indicates no current or previous infection with HSV-1 or HSV-2.
OD ratio 0.91 to 1.09 is equivocal HSV IgG antibody. Suggest a new specimen be collected and retested.
OD ratio > 1.10 is positive for IgG antibody to HSV. It indicates a current or previous infection with HSV-1 or HSV-2 or both.
Critical Ranges:  
Test Comments:
HSV-1 and HSV-2 share many cross-reacting antigens and a majority of the antibody produced in response to an initial infection is to share antigens. HSV-1 or HSV-2 antibody test results will not indicate the site of infection. This test is not intended to replace viral isolation.
Methodology: EIA
Clinical Significance:  
Custom Panel: No


Turn Around Time: 7 days
Days Performed: Monday
Sites Performed: Parkview Regional Medical Center
PHL Test Code: HERS
EPIC Test Code: IMO60
Alternate Test Names: Herpes IgG; Herpes Type 1 & 2 Specific IgG Abs; Herpeselect; HSV IgG 1 & 2
Included Tests:  
CPT Coding: 86695, 86696

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