Herpes Select 1 & 2 IgG Antibodies

Overview

  • EPIC Code:
  • IMO60
  • Soft Test Code:
  • HERS
Alternate Names
  • Herpes IgG
  • Herpes Type 1 & 2 Specific IgG Abs
  • Herpeselect
  • HSV 1/2 IgG Herpeselect
  • HSV IgG 1 & 2

Specimen Collection & Preparation

Specimen Requirements

1.0 mL Serum in a SST Gold Top Tube


Alternate Specimen

1.0 mL Serum from a Red Top Tube in a Plastic Vial


TransportAndStorage

48 hours Refrigerated
30 days Frozen


Specimen to be transported Refrigerated to PRMC within 48 hours of collection to be frozen by Immunology department to maintain specimen integrity until testing occurs. Do not transport Frozen.


Collection Instructions

 


Minimum Volume


Neonatal Volumne

Clinical Interpretation

Reference Range:

OD ratio < 0.90 indicates no detectable HSV IgG antibody. Indicates no current or previous infection with HSV-1 or HSV-2.
 
OD ratio 0.91 to 1.09 is equivocal HSV IgG antibody. Suggest a new specimen be collected and retested.
 
OD ratio > 1.10 is positive for IgG antibody to HSV. It indicates a current or previous infection with HSV-1 or HSV-2 or both.


Test Comments:

HSV-1 and HSV-2 share many cross-reacting antigens and a majority of the antibody produced in response to an initial infection is to share antigens. HSV-1 or HSV-2 antibody test results will not indicate the site of infection. This test is not intended to replace viral isolation.


Methodology:
  • Enzyme Immunoassay (EIA)

Production Schedule

Sites Performed
  • Parkview Regional Medical Center
Days Performed
Monday
Departments
  • Immunology
Turn Around Time

7 days


Coding & Compliance

CPT Coding

86695, 86696


Medical Necessity Documentation

Duplicate testing on this test is not acceptable per Medicare:  Testing to only be done every 365 days