Human Platelet Antigen 1 Genotype

Overview

  • EPIC Code:
  • LAB3191
  • Soft Test Code:
  • HPA1G
  • Send Out Test Code:
  • 10707
Alternate Names
  • HPA-1a(PLA Plt Ag) Genotype
  • Human Platelet Ag 1 Genotype
Clinical Significance

Human Platelet Antigen (HPA) polymorphism can lead to alloimmunization that clinically can manifest as neonatal alloimmune thrombocytopenia or post-transfusion thrombocytopenia purpura. HPA-1 genotyping allows screening for potential neonatal immunization in pregnancy


Specimen Collection & Preparation

Specimen Requirements

5.0 mL Whole Blood in (two) Lavender Top Tube(s) - EDTA 


Transport And Storage

7 days Ambient
14 days Refrigerated


Collection Instructions

 


Minimum Volume

1.0 mL Whole Blood


Neonatal Volume

Clinical Interpretation

Reference Range:

Refer to Interpretive Results


Methodology:
  • DNA-Based Capture Binding Assay
Clinical Significance

Human Platelet Antigen (HPA) polymorphism can lead to alloimmunization that clinically can manifest as neonatal alloimmune thrombocytopenia or post-transfusion thrombocytopenia purpura. HPA-1 genotyping allows screening for potential neonatal immunization in pregnancy


Production Schedule

Sites Performed
  • Quest - Chantilly to San Juan Capistrano
Days Performed
Tuesday
Departments
  • Sendouts - Clinical
Turn Around Time

2 to 4 days


Coding & Compliance

CDM

00917603


CPT Coding

81105