Mononucleosis Spot Test

Overview

  • EPIC Code:
  • IMO34
  • Soft Test Code:
  • MONO
Alternate Names
  • Heterophile Antibody Titer
  • Mono
  • Mononuclear Heterophile Test
  • Mononucleosis Screen
  • Monoscreen
  • Monospot
Clinical Significance

Infectious mononucleosis (IM), commonly called “mono” is an acute, generally self-limited, lymphoproliferative disease caused by Epstein-Barr virus (EBV). The diagnosis of IM is usually based on the evaluation of characteristic clinical, hematological, and serologic changes. Because other diseases may mimic the clinical and hematological symptoms of IM, serological testing is important for an accurate diagnosis. Serological diagnosis of IM is demonstrated by the presence of heterophile and EBV antibodies.


Specimen Collection & Preparation

Specimen Requirements:

-OR-

1.0 mL Whole Blood in a Lavender Top Tube - EDTA
Minimum Volume:
0.2 mL Whole Blood*

* This volume does not allow for repeat testing

Rejection Criteria:

Do not collect in a Gel Separator Tube (PST or SST)

Frozen whole blood

Grossly hemolyzed

Clotted specimens


Transport and Storage:
  • Ambient (18-24°C): 24 Hours
  • Refrigerated (2-8°C): 24 Hours

Clinical Interpretation

Reference Range:

Negative


Methodology:
  • Immunochromatographic
Clinical Significance

Infectious mononucleosis (IM), commonly called “mono” is an acute, generally self-limited, lymphoproliferative disease caused by Epstein-Barr virus (EBV). The diagnosis of IM is usually based on the evaluation of characteristic clinical, hematological, and serologic changes. Because other diseases may mimic the clinical and hematological symptoms of IM, serological testing is important for an accurate diagnosis. Serological diagnosis of IM is demonstrated by the presence of heterophile and EBV antibodies.


Production Schedule

Sites Performed
  • Parkview DeKalb Hospital
  • Parkview Huntington Hospital
  • Parkview Kosciusko Hospital
  • Parkview LaGrange Hospital
  • Parkview Noble Hospital
  • Parkview Randallia Hospital
  • Parkview Regional Medical Center
  • Parkview Southwest
  • Parkview Wabash Hospital
  • Parkview Whitley Hospital
Days Performed
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Departments
  • Hematology
Turn Around Time

Same Day/1 to 2 days


Stat Eligible

Coding & Compliance

CDM

01450326


CPT Coding

86308