Immunoglobulin G Subclasses Panel

Overview

  • EPIC Code:
  • IMO212
  • Soft Test Code:
  • IGGSB
  • Send Out Test Code:
  • 129192
Alternate Names
  • IgG Subclass 1, 2, 3, & 4
  • IgG Subclasses and Total IgG
  • IgG Subclasses Panel
Included Tests

IgG Subclass 1; IgG Subclass 2; IgG Subclass 3; IgG Subclass 4; IgG Total


Clinical Significance

Assess humoral immunity. Immunoglobulin G (IgG) is the most abundant immunoglobulin of extravascular liquids (65%) and of serum (70-75%). Antibodies of the IgG class are produced in response to most bacteria and viruses. IgG consists of two heavy and two light chains and contains less than 3% carbohydrate. IgG has four subclsses: IgG1, IgG2, IgG3, and IgG4. Both IgG1 and IgG3 bind firmly to the Fc receptors of phagocytic cells, activate killer monocytes (K cells), and cross the placenta


Specimen Collection & Preparation

Specimen Requirements

2.0 mL Serum from a Red Top Tube in a Plastic Vial


Transport And Storage

72 hours Ambient
10 days Refrigerated
30 days Frozen


Collection Instructions

 


Minimum Volume

1.0 mL Serum


Neonatal Volume

Clinical Interpretation

Reference Range:

Refer to Interpretive Results


Methodology:
  • Nephelometry
Clinical Significance

Assess humoral immunity. Immunoglobulin G (IgG) is the most abundant immunoglobulin of extravascular liquids (65%) and of serum (70-75%). Antibodies of the IgG class are produced in response to most bacteria and viruses. IgG consists of two heavy and two light chains and contains less than 3% carbohydrate. IgG has four subclsses: IgG1, IgG2, IgG3, and IgG4. Both IgG1 and IgG3 bind firmly to the Fc receptors of phagocytic cells, activate killer monocytes (K cells), and cross the placenta


Production Schedule

Sites Performed
  • Quest - Chantilly
Days Performed
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Departments
  • Sendouts - Clinical
Turn Around Time

1 to 2 days


Coding & Compliance

CPT Coding

82784, 82787 x 4