Immunoglobulin G Subclasses Panel

Included Tests

IgG Subclass 1; IgG Subclass 2; IgG Subclass 3; IgG Subclass 4; IgG Total

Clinical Significance

Assess humoral immunity. Immunoglobulin G (IgG) is the most abundant immunoglobulin of extravascular liquids (65%) and of serum (70-75%). Antibodies of the IgG class are produced in response to most bacteria and viruses. IgG consists of two heavy and two light chains and contains less than 3% carbohydrate. IgG has four subclsses: IgG1, IgG2, IgG3, and IgG4. Both IgG1 and IgG3 bind firmly to the Fc receptors of phagocytic cells, activate killer monocytes (K cells), and cross the placenta

Specimen Requirements

2.0 mL Serum from a Red Top Tube in a Plastic Vial

Transport And Storage

72 hours Ambient
10 days Refrigerated
30 days Frozen

Collection Instructions

 

Minimum Volume

1.0 mL Serum

Neonatal Volume

Reference Range:

Refer to Interpretive Results

Methodology:

• Nephelometry

Clinical Significance

Assess humoral immunity. Immunoglobulin G (IgG) is the most abundant immunoglobulin of extravascular liquids (65%) and of serum (70-75%). Antibodies of the IgG class are produced in response to most bacteria and viruses. IgG consists of two heavy and two light chains and contains less than 3% carbohydrate. IgG has four subclsses: IgG1, IgG2, IgG3, and IgG4. Both IgG1 and IgG3 bind firmly to the Fc receptors of phagocytic cells, activate killer monocytes (K cells), and cross the placenta

CPT Coding

82784, 82787 x 4