Immunoglobulin G Subclasses Panel

Last Modified: 8/15/2019 1:39:29 PM

Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:  
Specimen Requirements:

2.0 mL Serum from a Red Top Tube in a Plastic Vial

Collection Instructions:  
Minimum Volume: 1.0 mL Serum
Transport & Storage: Temperature/Stability: 72 hours Ambient
10 days Refrigerated
30 days Frozen
Rejection Criteria: Gross hemolysis • Lipemia
Reference Range:

Refer to Interpretive Results

Critical Ranges:  
Test Comments:  
Methodology: Nephelometry
Clinical Significance: Assess humoral immunity. Immunoglobulin G (IgG) is the most abundant immunoglobulin of extravascular liquids (65%) and of serum (70-75%). Antibodies of the IgG class are produced in response to most bacteria and viruses. IgG consists of two heavy and two light chains and contains less than 3% carbohydrate. IgG has four subclsses: IgG1, IgG2, IgG3, and IgG4. Both IgG1 and IgG3 bind firmly to the Fc receptors of phagocytic cells, activate killer monocytes (K cells), and cross the placenta
Custom Panel: No


Turn Around Time: 1 to 2 days
Days Performed: Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed: Quest - Chantilly
PHL Test Code: IGGSB
EPIC Test Code: IMO212
Send Out Test Code: 129192
Alternate Test Names: IgG Subclass 1, 2, 3, & 4; IgG Subclasses and Total IgG; IgG Subclasses Panel
Included Tests: IgG Subclass 1; IgG Subclass 2; IgG Subclass 3; IgG Subclass 4; IgG Total
CPT Coding: 82784, 82787 x 4

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