Last Modified:
8/21/2023 1:35:15 PM
Medical Necessity Documentation:
Client Notes:
Patient Preparation:
It is preferable for the patient to be off medications for three days prior to collection. Patient should avoid tobacco, tea, coffee, for three days prior to specimen collection. Common antihypertensives (diuretics, ACE inhibitors, calcium channel blockers, alpha and beta blockers) cause minimal or no interference. Medications which are alpha agonists (Aldomet), alpha blockers (Dibenzyline) should be avoided 18-24 hours prior to specimen collection
Specimen Requirements:
5.0 mL Urine aliquot from a well mixed 24 hour Urine Collection in a Plastic Container
Collection Instructions:
Order must include the patients age on Order and Urine Vial
1. When starting the 24-hour period, urinate and discard (throw-away) this specimen. NOTE THE TIME
2. From that time on, collect all urine by urinating into a clean container and transfer into the provided container.
DO NOT URINATE DIRECTLY INTO CONTAINER.
3. Try to pass the last urine just prior to the end of the 24 hour period. Add this urine into the container.
4. Urine Specimen should be kept refrigerated during and after collection.
For patient collection instruction sheet see Addendum D
For Spanish patient collection instruction sheet see Addendum D
For Burmese patient collection instruction sheet see Addendum D
For Arabic patient collection instruction sheet see Addendum D
Minimum Volume:
1.5 mL Urine
Transport & Storage: Temperature/Stability:
Preserved Urine
10 days Ambient
14 days Refrigerated
90 days Frozen
Unpreserved Urine
Unacceptable Ambient
Unacceptable Refrigerated
30 days Frozen
Rejection Criteria:
Urine collected with boric acid
Reference Range:
Metanephrines, 24-Hour Urine |
|
|
Age |
Reference Range |
UOM |
3 months-4 years |
25-117 |
mcg/24 h |
5-9 years |
11-139 |
mcg/24 h |
10-13 years |
51-275 |
mcg/24 h |
14-17 years |
40-189 |
mcg/24 h |
18-29 years |
25-222 |
mcg/24 h |
30-39 years |
36-190 |
mcg/24 h |
40-49 years |
58-203 |
mcg/24 h |
≥50 years |
90-315 |
mcg/24 h |
|
|
|
Normetanephrines, 24-Hour Urine |
|
|
3 months-4 years |
54-249 |
mcg/24 h |
5-9 years |
31-398 |
mcg/24 h |
10-13 years |
67-503 |
mcg/24 h |
14-17 years |
69-531 |
mcg/24 h |
18-29 years |
40-412 |
mcg/24 h |
30-39 years |
35-482 |
mcg/24 h |
40-49 years |
88-649 |
mcg/24 h |
≥50 years |
122-676 |
mcg/24 h |
|
|
|
Metanephrines, Total 24-Hour Urine |
|
|
3 months-4 years |
79-345 |
mcg/24 h |
5-9 years |
49-408 |
mcg/24 h |
10-13 years |
110-714 |
mcg/24 h |
14-17 years |
107-741 |
mcg/24 h |
18-29 years |
94-604 |
mcg/24 h |
30-39 years |
115-695 |
mcg/24 h |
40-49 years |
182-739 |
mcg/24 h |
≥50 years |
224-832 |
mcg/24 h |
Critical Ranges:
Test Comments:
Methodology:
Liquid Chromatography/Tandem Mass Spectrometry
Clinical Significance:
Test is useful in the evaluation of pheochromocytoma.
Documentation:
Custom Panel:
No
PRODUCTION SCHEDULE
Turn Around Time:
3 to 5 days
Days Performed:
Monday, Tuesday, Wednesday, Thursday, Friday
Sites Performed:
Quest - Chantilly
PHL Test Code:
MET2
EPIC Test Code:
LAB409
Send Out Test Code:
14962
Alternate Test Names:
Metanephrines Total & Fractionated Ur; Metanephrines, Fractionated 24-Hour Urine
Included Tests:
Metanepharines; Normetanephrines; Total Metanepharines
CPT Coding:
83835
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