Disseminated Intravascular Coagulation Panel

Last Modified: 6/1/2022 1:27:21 PM

  Medicare Medical Necessity Restrictions May Apply
Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:  
Specimen Requirements: Platelet Poor Plasma from a 2.7 mL Whole Blood in a Blue Top Tube - 3.2% Buffered Sodium Citrate in a Plastic Vial
2.7 mL Whole Blood in a Blue Top Tube -  3.2% Buffered Sodium Citrate
3.0 mL Whole Blood in a Lavender Top Tube - EDTA
Collection Instructions: Blue Top Tube(s) Collection
Correct ratio of Blood to Citrate is critical (9:1). Specimens must be filled within +/- 10% of stated volume.Specimens must be filled appropriately see this example

If a Blue Top Tube is collected utilizing a butterfly, a Blue Discard Tube must be drawn first to remove air from the line. If this is not done, the Blue Top Tube will not be filled properly due to the vacuum in tube and a redraw will be required

*Heparinized Patient specimens must be spun within 1 hour of collection

Note: Collection of blood for coagulation testing through intravenous lines that have been previously flushed with heparin should be avoided, if possible. 
If the blood must be drawn through an indwelling catheter, possible heparin contamination and specimen dilution should be considered. 
When obtaining specimsn from indwelling lines that may contain heparin, the line should be flushed with 5mL of saline, and the first 5 mL of blood or 6-times the line volume
(dead space volume of the catheter) be drawn off and discarded before the coagulation tube is filled. For those samples collected from a normal saline lock (capped off venous port) twice the dead space volume of the catheter and extension set should be discarded.

Platelet Poor Plasma Blue Top 1 specific collection and processing instructions click here 
Platelet Poor Plasma 

Lavendar Top Tube
Mix tube by inversion 5 times

Do not centrifuge

Specimens must not be clotted and cannot contain microclots. Overfilling or underfilling may allow blood to clot. Specimens may be rejected due to WBC deterioration resulting from improper storage or age of specimen

For slide preparation see Addendum D

Transport & Storage: Temperature/Stability:

Platelet Poor Plasma: 
Unfractionated heparinized patient 4 hour Ambient Blue

Non-heparinized patient 24 hours Ambient 

  This tube must be transported to testing laboratory within 45 minutes from collection. If this is not a possibility follow the forllowing steps: 
1. Heparinized Patient specimens must be spun wihtin 1 hour of collection, following these Platelet Poor Plasma preparation instructions 
2. Send the "frozen" platelet poor plasma & primary tube to the testing laboratory
3. Contact the laboratory at 266-1500 option 1, to notify PRMC laboratory that he specimen is coming

Blue Top Tube (whole blood):
Unfractionated heparinized patient 4 hour Ambient 

Non-heparinized patient 24 hours Ambient 

Lavendar Top Tube:
24 hours Ambient
72 hours Refrigerated

Rejection Criteria: Frozen in a Frost Free Freezer; under filled tubes; 3.8% Sodium Citrate; clotted; underfilled; HCT >55%; cell volume > 1/2 the tube volume; Re-frozen; Thawed specimens
Reference Range: Refer to Individual Tests
Critical Ranges:  
Test Comments:  
Methodology: Multiple
Clinical Significance:  
Custom Panel: No


Stat Eligible: Yes
Days Performed: Sunday, Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed: Parkview Dekalb, Parkview Hospital Randallia, Parkview Huntington, Parkview LaGrange, Parkview Noble, Parkview Regional Medical Center, Parkview Wabash, Parkview Warsaw , Parkview Whitley
PHL Test Code: DIC2
EPIC Test Code: LAB2672
Alternate Test Names: DIC
Included Tests:
Activated Partial Thromboplastin Time (APTT);  D-Dimer Quantitative; Fibrinogen; INR; Platelet Count (PLT); Prothrombin Time (PT)   
CPT Coding: 85049, 85379, 85384, 85610, 85730

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