Gamma-Hydroxybutyric Acid Screen, Urine

Overview

  • EPIC Code:
  • LAB3064
  • Soft Test Code:
  • GHA
  • Send Out Test Code:
  • 37653 (9326U)
Alternate Names
  • Date Rape Drug
  • Gamma-Hydroxybutyrate
  • Gamma-Hydroxybutyrate Acid
  • GHB
  • Sodium Oxybate
  • Xyrem
Clinical Significance

Forensic Analysis; Exclusion Screen


Specimen Collection & Preparation

Specimen Requirements

5.0 mL Urine Collection in a Non-Sterile Yellow Capped Container


Transport And Storage

7 days Ambient
7 days Refrigerated
21 days Frozen


Collection Instructions

preservative-free


Minimum Volume

2.8 mL Urine


Neonatal Volume

Clinical Interpretation

Reference Range:

Gamma-Hydroxybutyric Acid    2.0 mcg/mL
  GHB; Gamma-Hydroxybutyrate

Endogenous GHB levels in healthy adults have been determined to range up to 6.6 mcg/mL. Sixteen healthy adults given a single oral dose (50 mg/kg) developed urine levels averaging: 168 mcg/mL during the 0 to 3 hour post-dose interval, 157 mcg/mL during the 3 to 6 hour period and 3.8 mcg/mL for the 6 to 12 hour window. The value reported for GHB is a total of GHB and its lactone (GBL) in the specimen


Test Comments:

If screen is positive, confirmatory testing will be added automatically at no additional charge.


Methodology:
  • Gas Chromatography / Mass Spectrometry (GC/MS)
Clinical Significance

Forensic Analysis; Exclusion Screen


Production Schedule

Sites Performed
  • Quest - Chantilly to NMS Laboratories
Days Performed
Tuesday
Thursday
Departments
  • Sendouts - Clinical
Turn Around Time

4 days


Coding & Compliance

CDM

00918040


CPT Coding

80307