Gamma-Hydroxybutyric Acid Screen, Urine

Last Modified: 3/4/2021 12:47:22 PM

Medical Necessity Documentation:  
Client Notes:  
Patient Preparation:  
Specimen Requirements:

5.0 mL Urine Collection in a Non-Sterile Yellow Capped Container

Collection Instructions: preservative-free
Minimum Volume: 2.8 mL Urine
Transport & Storage: Temperature/Stability: 7 days Ambient
7 days Refrigerated
21 days Frozen
Reference Range: Gamma-Hydroxybutyric Acid    2.0 mcg/mL
  GHB; Gamma-Hydroxybutyrate

Endogenous GHB levels in healthy adults have been determined to range up to 6.6 mcg/mL. Sixteen healthy adults given a single oral dose (50 mg/kg) developed urine levels averaging: 168 mcg/mL during the 0 to 3 hour post-dose interval, 157 mcg/mL during the 3 to 6 hour period and 3.8 mcg/mL for the 6 to 12 hour window. The value reported for GHB is a total of GHB and its lactone (GBL) in the specimen
Critical Ranges:  
Test Comments: If screen is positive, confirmatory testing will be added automatically at no additional charge.
Methodology: GC/MS
Clinical Significance: Forensic Analysis; Exclusion Screen
Custom Panel: No


Turn Around Time: 4 days
Days Performed: Tuesday, Thursday
Sites Performed: Quest - Chantilly to NMS Laboratories
PHL Test Code: GHA
EPIC Test Code: LAB3064
Send Out Test Code: 37653 (9326U)
Alternate Test Names: Date Rape Drug; Gamma-Hydroxybutyrate; Gamma-Hydroxybutyrate Acid; GHB ; Sodium Oxybate; Xyrem
Included Tests:  
CPT Coding: 80307

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