Kappa / Lambda Light Chains, Total, with Calculation

Last Modified: 9/17/2018 7:09:32 AM

Specimen Requirements: 2.0 mL aliquot from a well mixed 24 hour Urine Collection in a Plastic ContainerContainer
Collection Instructions:

Order must include the patients age and gender

1. When starting the 24-hour period, urinate and discard (throw-away) this specimen. NOTE THE TIME
2. From that time on, collect all urine by urinating into a clean container and transfer into the provided container. 
3. Try to pass the last urine just prior to the end of the 24 hour period. Add this urine into the container. 
4. Urine Specimen should be kept refrigerated during and after collection. 

For patient collection instruction sheet see Addendum D
For Spanish patient collection instruction sheet see Addendum D
For Burmese patient collection instruction sheet see Addendum D

Minimum Volume: 0.5 mL Urine
Transport & Storage: Temperature/Stability: 12 hours Ambient
7 days Refrigerated
Reference Range:

Measured Kappa Chains                           < 2.00 mg/dL
Measured Lambda Chains < 2.00 mg/dL

Methodology: Nephelometric
Clinical Significance: Polyclonal immunoglobulin light chains (kappa and lambda) normally occur in a ratio of 2: 1, whereas monoclonal immunoglobulin light chains exhibit only one type of light chain, either kappa or lambda. A kappa: Lambda ratio outside of 2: 1 is an indication fo monoclonal gammopathy.
Custom Panel: No


Turn Around Time: 4 to 8 days
Days Performed: Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Sites Performed: Quest - Chantilly
PHL Test Code: MSOT
Send Out Test Code: 17300
Alternate Test Names: Immunoglobulin Free Light Chains
CPT Coding: 83883 x 2

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